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Applications of Phosphate Modification and Labeling to Study (m)RNA Caps.Triazole-containing monophosphate mRNA cap analogs as effective translation inhibitorsSynthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes.Distinct features of cap binding by eIF4E1b proteinsTwo-headed tetraphosphate cap analogs are inhibitors of the Dcp1/2 RNA decapping complex.A novel route for preparing 5' cap mimics and capped RNAs: phosphate-modified cap analogues obtained via click chemistrySynthesis and evaluation of fluorescent cap analogues for mRNA labelling.Cap analogs modified with 1,2-dithiodiphosphate moiety protect mRNA from decapping and enhance its translational potential.mRNA transcript therapy.Knockdown of eukaryotic translation initiation factor 4E suppresses cell growth and invasion, and induces apoptosis and cell cycle arrest in a human lung adenocarcinoma cell line.Mechanism of action of mRNA-based vaccines.Design and Facile Synthesis of New Dinucleotide Cap Analog Containing Both 2' and 3'-OH Modification on M⁷Guanosine Moiety.mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translationTherapeutic Applications of Targeted Alternative Splicing to Cancer Treatment.
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
Potential therapeutic applications of RNA cap analogs.
@en
type
label
Potential therapeutic applications of RNA cap analogs.
@en
prefLabel
Potential therapeutic applications of RNA cap analogs.
@en
P2860
P50
P356
P1476
Potential therapeutic applications of RNA cap analogs
@en
P2093
Malwina Strenkowska
P2860
P304
P356
10.4155/FMC.13.96
P577
2013-06-01T00:00:00Z