Genome-based cancer therapeutics: targets, kinase drug resistance and future strategies for precision oncology.

Genome-based cancer therapeutics: targets, kinase drug resistance and future strategies for precision oncology.

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http://www.wikidata.org/entity/Q38117994
Ten things you should know about protein kinases: IUPHAR Review 14Recent findings and future directions for interpolar mitotic kinesin inhibitors in cancer therapyDistinctive Behaviors of Druggable Proteins in Cellular NetworksPolypharmacology in Precision Oncology: Current Applications and Future ProspectsValidation and utilisation of high-coverage next-generation sequencing to deliver the pharmacological audit trail'Big data' approaches for novel anti-cancer drug discovery.Resistance to HSP90 inhibition involving loss of MCL1 addiction.Approaches for measuring signalling plasticity in the context of resistance to targeted cancer therapies.Therapeutic opportunities within the DNA damage response.Comprehensive transcriptomic analysis of molecularly targeted drugs in cancer for target pathway evaluation.Resistance of Cancer Cells to Targeted Therapies Through the Activation of Compensating Signaling Loops.Clinical massively parallel next-generation sequencing analysis of 409 cancer-related genes for mutations and copy number variations in solid tumours.In search of AKT kinase inhibitors as anticancer agents: structure-based design, docking, and molecular dynamics studies of 2,4,6-trisubstituted pyridines.KRDS: a web server for evaluating drug resistance mutations in kinases by molecular docking.Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells.
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Genome-based cancer therapeutics: targets, kinase drug resistance and future strategies for precision oncology.

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http://www.wikidata.org/entity/Q38117994
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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Genome-based cancer therapeuti ...... tegies for precision oncology.
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type
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Genome-based cancer therapeuti ...... tegies for precision oncology.
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prefLabel
Genome-based cancer therapeuti ...... tegies for precision oncology.
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P1476
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Genome-based cancer therapeuti ...... tegies for precision oncology.
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10.1016/J.COPH.2013.06.004
P433
P478
P50
P577
P698