Origins of aberrant DNA methylation in acute myeloid leukemia.
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DNA Methyltransferase Activity Assays: Advances and ChallengesEpigenetic Guardian: A Review of the DNA Methyltransferase DNMT3A in Acute Myeloid Leukaemia and Clonal Haematopoiesis.Increasing TIMP3 expression by hypomethylating agents diminishes soluble MICA, MICB and ULBP2 shedding in acute myeloid leukemia, facilitating NK cell-mediated immune recognitionThymoquinone exerts potent growth-suppressive activity on leukemia through DNA hypermethylation reversal in leukemia cells.Enhancers of Polycomb EPC1 and EPC2 sustain the oncogenic potential of MLL leukemia stem cellsDNMT3A and IDH mutations in acute myeloid leukemia and other myeloid malignancies: associations with prognosis and potential treatment strategiesLoss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis.Epigenetic modifications of splicing factor genes in myelodysplastic syndromes and acute myeloid leukemia.Mitogen-activated protein kinase binding protein 1 (MAPKBP1) is an unfavorable prognostic biomarker in cytogenetically normal acute myeloid leukemia.Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer riskPredicting DNA Methylation State of CpG Dinucleotide Using Genome Topological Features and Deep Networks.A clinical measure of DNA methylation predicts outcome in de novo acute myeloid leukemiaAn integrative and comparative study of pan-cancer transcriptomes reveals distinct cancer common and specific signatures.Clinical implications of genome-wide DNA methylation studies in acute myeloid leukemia.Do age-associated DNA methylation changes increase the risk of malignant transformation?Imprinted genes in myeloid lineage commitment in normal and malignant hematopoiesis.Perspectives for therapeutic targeting of gene mutations in acute myeloid leukaemia with normal cytogenetics.Nivolumab for the treatment of classical Hodgkin lymphoma after failure of autologous stem cell transplant and brentuximab.Binding of 14-3-3 reader proteins to phosphorylated DNMT1 facilitates aberrant DNA methylation and gene expression.Upregulation of TET activity with ascorbic acid induces epigenetic modulation of lymphoma cells.Silencing of GATA3 defines a novel stem cell-like subgroup of ETP-ALL.On the potential role of DNMT1 in acute myeloid leukemia and myelodysplastic syndromes: not another mutated epigenetic driver.Methyl-CpG/MBD2 Interaction Requires Minimum Separation and Exhibits Minimal Sequence Specificity.Possible role of intragenic DNA hypermethylation in gene silencing of the tumor suppressor gene NR4A3 in acute myeloid leukemia.Hydroquinone-induced FOXP3-ADAM17-Lyn-Akt-p21 signaling axis promotes malignant progression of human leukemia U937 cells.Genetic variants involved in oxidative stress, base excision repair, DNA methylation, and folate metabolism pathways influence myeloid neoplasias susceptibility and prognosis.Targeting DNA hypermethylation: computational modeling of DNA demethylation treatment of acute myeloid leukemia.DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia.Redistribution of cell cycle by arsenic trioxide is associated with demethylation and expression changes of cell cycle related genes in acute promyelocytic leukemia cell line (NB4).Targeting histone methyltransferase and demethylase in acute myeloid leukemia therapy.Evaluating the breast cancer predisposition role of rare variants in genes associated with low-penetrance breast cancer risk SNPs.Epigenetic drug combination induces remission in mouse xenograft models of pediatric acute myeloid leukemia.Ensemble-Based Virtual Screening and Experimental Validation of Inhibitors Targeting a Novel Site of Human DNMT1.Incidence and risk of hematologic toxicities with hypomethylating agents in the treatment of myelodysplastic syndromes and acute myeloid leukopenia: A systematic review and meta-analysis
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Origins of aberrant DNA methylation in acute myeloid leukemia.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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Origins of aberrant DNA methylation in acute myeloid leukemia.
@en
type
label
Origins of aberrant DNA methylation in acute myeloid leukemia.
@en
prefLabel
Origins of aberrant DNA methylation in acute myeloid leukemia.
@en
P2093
P2860
P356
P1433
P1476
Origins of aberrant DNA methylation in acute myeloid leukemia.
@en
P2093
C Müller-Tidow
W E Berdel
P2860
P2888
P356
10.1038/LEU.2013.242
P577
2013-08-20T00:00:00Z
P5875
P6179
1051355543