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To Know How a Gene Works, We Need to Redefine It First but then, More Importantly, to Let the Cell Itself Decide How to Transcribe and Process Its RNAsThe Evolution of Aggregative Multicellularity and Cell-Cell Communication in the DictyosteliaEmerging strategies for RNA interference (RNAi) applications in insectsA MultiSite Gateway Toolkit for Rapid Cloning of Vertebrate Expression Constructs with Diverse Research Applications.Living Cell Microarrays: An Overview of ConceptsKey enzymes and proteins of crop insects as candidate for RNAi based gene silencingRAS Synthetic Lethal Screens Revisited: Still Seeking the Elusive Prize?Aerosol Delivery of siRNA to the Lungs. Part 1: Rationale for Gene Delivery SystemsQuantitative phosphoproteomics reveals new roles for the protein phosphatase PP6 in mitotic cellsT-REX on-demand redox targeting in live cells.Improved knockdown from artificial microRNAs in an enhanced miR-155 backbone: a designer's guide to potent multi-target RNAiDistinct roles for primate caudate dopamine D1 and D2 receptors in visual discrimination learning revealed using shRNA knockdown.siRNA Delivery Strategies: A Comprehensive Review of Recent Developments.Genome-wide gene expression patterns in dikaryon of the basidiomycete fungus Pleurotus ostreatus.Development of siRNA payloads to target KRAS-mutant cancer.CRISPR-mediated direct mutation of cancer genes in the mouse liverApplications of RNA interference high-throughput screening technology in cancer biology and virologyChoosing the Right Tool for the Job: RNAi, TALEN, or CRISPR.A simplified and versatile system for the simultaneous expression of multiple siRNAs in mammalian cells using Gibson DNA AssemblyState-of-the-art human gene therapy: part II. Gene therapy strategies and clinical applications.Fluorescent carbon dots as an efficient siRNA nanocarrier for its interference therapy in gastric cancer cellsImmunoblot screening of CRISPR/Cas9-mediated gene knockouts without selection.Off Target, but Sequence-Specific, shRNA-Associated Trans-Activation of Promoter Reporters in Transient Transfection Assays.A streamlined method for the design and cloning of shRNAs into an optimized Dox-inducible lentiviral vector.Tissue-specific tumorigenesis: context matters.Prediction of potent shRNAs with a sequential classification algorithm.Aerosol Delivery of siRNA to the Lungs. Part 2: Nanocarrier-based Delivery SystemsCell Type-Specific and Inducible PTEN Gene Silencing by a Tetracycline Transcriptional Activator-Regulated Short Hairpin RNA.On-Demand Targeting: Investigating Biology with Proximity-Directed Chemistry.In vivo RNAi screens: concepts and applications.CXCL12/CXCR4 axis induces proliferation and invasion in human endometrial cancer.Loss-of-function genetic tools for animal models: cross-species and cross-platform differences.Therapeutic face of RNAi: in vivo challenges.RNAi in the mouse: rapid and affordable gene function studies in a vertebrate system.RNA aptamers as genetic control devices: the potential of riboswitches as synthetic elements for regulating gene expression.RNA interference for multiple myeloma therapy: targeting signal transduction pathways.The cancer epigenome: Concepts, challenges, and therapeutic opportunities.Knockdown of β-catenin by siRNA influences proliferation, apoptosis and invasion of the colon cancer cell line SW480Studying Protein Function and the Role of Altered Protein Expression by Antibody Interference and Three-dimensional Reconstructions.Drug discovery in advanced prostate cancer: translating biology into therapy.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Stable RNA interference rules for silencing.
@en
type
label
Stable RNA interference rules for silencing.
@en
prefLabel
Stable RNA interference rules for silencing.
@en
P2860
P356
P1433
P1476
Stable RNA interference rules for silencing.
@en
P2093
Scott W Lowe
P2860
P2888
P356
10.1038/NCB2895
P577
2014-01-01T00:00:00Z
P6179
1040028427