The bile acid TGR5 membrane receptor: from basic research to clinical application.
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How do patients' clinical phenotype and the physiological mechanisms of the operations impact the choice of bariatric procedure?Bile acids: emerging role in management of liver diseasesBile acids are nutrient signaling hormonesBile acids, obesity, and the metabolic syndromeGut chemosensing: implications for disease pathogenesisThe role of bile salts in liver regenerationBile acid signaling in metabolic disease and drug therapyIdentification of key amino acid residues in the hTGR5-nomilin interaction and construction of its binding model.The physiology underlying Roux-en-Y gastric bypass: a status report.Systematic review: bile acids and intestinal inflammation-luminal aggressors or regulators of mucosal defence?Functional and structural features of cholangiocytes in health and disease.Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 3. Untargeted metabolomics.The human gut sterolbiome: bile acid-microbiome endocrine aspects and therapeutics.The G-Protein-Coupled Bile Acid Receptor Gpbar1 (TGR5) Inhibits Gastric Inflammation Through Antagonizing NF-κB Signaling PathwayA metabolomic perspective of griseofulvin-induced liver injury in mice.The G-protein-coupled bile acid receptor Gpbar1 (TGR5) suppresses gastric cancer cell proliferation and migration through antagonizing STAT3 signaling pathwayMembrane bile acid receptor TGR5 predicts good prognosis in ampullary adenocarcinoma patients with hyperbilirubinemiaThe Gut Microbiota as a Therapeutic Target in IBD and Metabolic Disease: A Role for the Bile Acid Receptors FXR and TGR5.Characterization of AQPs in Mouse, Rat, and Human Colon and Their Selective Regulation by Bile Acids.OL3, a novel low-absorbed TGR5 agonist with reduced side effects, lowered blood glucose via dual actions on TGR5 activation and DPP-4 inhibition.Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives.Bile salt receptor TGR5 is highly expressed in esophageal adenocarcinoma and precancerous lesions with significantly worse overall survival and gender differences.The role of bile acids in functional GI disorders.Bile acid malabsorption in inflammatory bowel disease.Role of taurine in the pathogenesis of obesity.Therapeutic Targets in Polycystic Liver Disease.Could burning fat start with a brite spark? Pharmacological and nutritional ways to promote thermogenesis.Chenodeoxycholic acid requires activation of EGFR, EPAC, and Ca2+ to stimulate CFTR-dependent Cl- secretion in human colonic T84 cells.TGR5 contributes to hepatic cystogenesis in rodents with polycystic liver diseases through cyclic adenosine monophosphate/Gαs signaling.Lithocholic acid attenuates cAMP-dependent Cl- secretion in human colonic epithelial T84 cells.Gastroparesis and lipid metabolism-associated dysbiosis in Wistar-Kyoto rats.Involvement of glucagon-like peptide-1 in the glucose-lowering effect of metformin.The Contributing Role of Bile Acids to Metabolic Improvements After Obesity and Metabolic Surgery.Mechanisms of Action of Surgical Interventions on Weight-Related Diseases: the Potential Role of Bile Acids.Evidence connecting old, new and neglected glucose-lowering drugs to bile acid-induced GLP-1 secretion: A review.Structural assemblies of the di- and oligomeric G-protein coupled receptor TGR5 in live cells: an MFIS-FRET and integrative modelling study.Mechanisms of cholangiocyte responses to injury.Macrophage Activation by Ursolic and Oleanolic Acids during Mycobacterial Infection.TGR5 in the Cholangiociliopathies.Vertical sleeve gastrectomy activates GPBAR-1/TGR5 to sustain weight loss, improve fatty liver, and remit insulin resistance in mice
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The bile acid TGR5 membrane receptor: from basic research to clinical application.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
The bile acid TGR5 membrane receptor: from basic research to clinical application.
@en
type
label
The bile acid TGR5 membrane receptor: from basic research to clinical application.
@en
prefLabel
The bile acid TGR5 membrane receptor: from basic research to clinical application.
@en
P2860
P1476
The bile acid TGR5 membrane receptor: from basic research to clinical application.
@en
P2093
Alan F Hofmann
Henri Duboc
P2860
P304
P356
10.1016/J.DLD.2013.10.021
P50
P577
2014-01-09T00:00:00Z