Molecular insights into NF2/Merlin tumor suppressor function.
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Hepatocellular carcinoma mouse models: Hepatitis B virus-associated hepatocarcinogenesis and haploinsufficient tumor suppressor genesTumors of the neural crest: Common themes in development and cancerThe importance of nerve microenvironment for schwannoma development.A critical role for NF2 and the Hippo pathway in branching morphogenesisEpithelial junctions and Rho family GTPases: the zonular signalosome.Childhood neurofibromatosis type 2 (NF2) and related disorders: from bench to bedside and biologically targeted therapies.Merlin status regulates p75(NTR) expression and apoptotic signaling in Schwann cells following nerve injury.Merlin is required for coordinating proliferation of two stem cell lineages in the Drosophila testis.Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathwayNeurofibromatosis-related tumors: emerging biology and therapies.Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cellsThe Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation.Informative gene selection and the direct classification of tumors based on relative simplicity.Neuron-Specific Deletion of the Nf2 Tumor Suppressor Impairs Functional Nerve Regeneration.Merlin/NF2 Suppresses Pancreatic Tumor Growth and Metastasis by Attenuating the FOXM1-Mediated Wnt/β-Catenin Signaling.Hippo transducer TAZ promotes epithelial mesenchymal transition and supports pancreatic cancer progressionMolecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets.The mammalian Hippo pathway: regulation and function of YAP1 and TAZ.Control of Proliferation and Cancer Growth by the Hippo Signaling Pathway.Clinical and molecular predictors of mortality in neurofibromatosis 2: a UK national analysis of 1192 patients.Merlin controls the repair capacity of Schwann cells after injury by regulating Hippo/YAP activity.Fgf10-Hippo Epithelial-Mesenchymal Crosstalk Maintains and Recruits Lung Basal Stem Cells.MicroRNA-335-5p is a potential suppressor of metastasis and invasion in gastric cancer.Essential signaling in NF2 loss-related tumours: the therapeutic potential of CRL4DCAF1 and mTOR combined inhibition.Targeted next-generation sequencing for differential diagnosis of neurofibromatosis type 2, schwannomatosis, and meningiomatosis.Targeting the Hippo Pathway Is a New Potential Therapeutic Modality for Malignant Mesothelioma.CXCR4: A new player in vestibular schwannoma pathogenesis.Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2.Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss-Driven Tumorigenesis.NF2 signaling pathway plays a pro-apoptotic role in β-adrenergic receptor stimulated cardiac myocyte apoptosis.Neurofibromatosis type 2 tumor suppressor protein is expressed in oligodendrocytes and regulates cell proliferation and process formation.NF2/Merlin Inactivation and Potential Therapeutic Targets in Mesothelioma.Activation mechanisms of the Hippo kinase signaling cascade
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Molecular insights into NF2/Merlin tumor suppressor function.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Molecular insights into NF2/Merlin tumor suppressor function.
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type
label
Molecular insights into NF2/Merlin tumor suppressor function.
@en
prefLabel
Molecular insights into NF2/Merlin tumor suppressor function.
@en
P2860
P1433
P1476
Molecular insights into NF2/Merlin tumor suppressor function.
@en
P2093
Filippo G Giancotti
Jonathan Cooper
P2860
P304
P356
10.1016/J.FEBSLET.2014.04.001
P407
P577
2014-04-12T00:00:00Z