Involvement of the amino-terminal beta-hairpin of the Aspergillus ribotoxins on the interaction with membranes and nonspecific ribonuclease activity.
about
Cytotoxic ribonucleases: molecular weapons and their targetsTyr-48, a conserved residue in ribotoxins, is involved in the RNA-degrading activity of alpha-sarcin.Fungal ribotoxins: molecular dissection of a family of natural killers.A deimmunised form of the ribotoxin, α-sarcin, lacking CD4+ T cell epitopes and its use as an immunotoxin warhead.Hirsutellin A: A Paradigmatic Example of the Insecticidal Function of Fungal Ribotoxins.Leucine 145 of the ribotoxin alpha-sarcin plays a key role for determining the specificity of the ribosome-inactivating activity of the protein.Arginine 121 is a crucial residue for the specific cytotoxic activity of the ribotoxin alpha-sarcin.Conserved asparagine residue 54 of alpha-sarcin plays a role in protein stability and enzyme activity.The insecticidal protein hirsutellin A from the mite fungal pathogen Hirsutella thompsonii is a ribotoxin.Deletion of the NH2-terminal beta-hairpin of the ribotoxin alpha-sarcin produces a nontoxic but active ribonuclease.
P2860
Q28189322-74BB49A2-2A3F-413E-A17E-A11DAEA8BEEAQ34532818-F73625D2-DE2D-4605-AC8E-32C76D514E36Q36718512-11779CCF-2AA7-4B77-8777-46E73DE05576Q37367958-2408603F-1DDD-4501-A821-189CE3104AD0Q38606154-610FB82D-A063-42BD-8D46-A2792E0CF623Q41908955-61182576-CC22-49B9-A8C2-D487439D0DDAQ43815486-6E67A4FE-156C-4BF2-BDBA-E9E36500A7F9Q45226426-FDA270CB-F780-4839-A41E-96C78A8481C0Q52687942-44C25A3A-EE27-4711-9222-88BBE831C7B3Q54548929-DD2675D8-3727-4E76-A3F7-E17DA3D1EC2B
P2860
Involvement of the amino-terminal beta-hairpin of the Aspergillus ribotoxins on the interaction with membranes and nonspecific ribonuclease activity.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Involvement of the amino-termi ...... pecific ribonuclease activity.
@en
type
label
Involvement of the amino-termi ...... pecific ribonuclease activity.
@en
prefLabel
Involvement of the amino-termi ...... pecific ribonuclease activity.
@en
P2093
P2860
P50
P356
P1433
P1476
Involvement of the amino-termi ...... specific ribonuclease activity
@en
P2093
P2860
P304
P356
10.1110/PS.9601
P577
2001-08-01T00:00:00Z