Activated nuclear metabotropic glutamate receptor mGlu5 couples to nuclear Gq/11 proteins to generate inositol 1,4,5-trisphosphate-mediated nuclear Ca2+ release.
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Nuclear GPCRs in cardiomyocytes: an insider's view of β-adrenergic receptor signalingDysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and AutismCalcium-sensing receptor biosynthesis includes a cotranslational conformational checkpoint and endoplasmic reticulum retentionCalcium signaling in synapse-to-nucleus communicationMolecular Insights into Metabotropic Glutamate Receptor Allosteric ModulationLocation-dependent signaling of the group 1 metabotropic glutamate receptor mGlu5.Cysteine (C)-x-C receptor 4 undergoes transportin 1-dependent nuclear localization and remains functional at the nucleus of metastatic prostate cancer cellsShuttling and translocation of heterotrimeric G proteins and Ras.Functional G protein-coupled receptors on nuclei from brain and primary cultured neuronsActivation of intracellular metabotropic glutamate receptor 5 in striatal neurons leads to up-regulation of genes associated with sustained synaptic transmission including Arc/Arg3.1 protein.Comprehensive Immunolocalization Studies of a Putative Serotonin Receptor from the Alimentary Canal of Aedes aegypti Larvae Suggest Its Diverse Roles in Digestion and HomeostasisIntracellular mGluR5 plays a critical role in neuropathic painIntracrine endothelin signaling evokes IP3-dependent increases in nucleoplasmic Ca²⁺ in adult cardiac myocytes.Intracellular metabotropic glutamate receptor 5 (mGluR5) activates signaling cascades distinct from cell surface counterpartsMechanisms Associated with Activation of Intracellular Metabotropic Glutamate Receptor, mGluR5.Intracellular mGluR5 can mediate synaptic plasticity in the hippocampus.G protein-coupled receptor signalling in the cardiac nuclear membrane: evidence and possible roles in physiological and pathophysiological function.Role of the nuclear envelope in calcium signalling.Optogenetic reporters: Fluorescent protein-based genetically encoded indicators of signaling and metabolism in the brainThe roles played by highly truncated splice variants of G protein-coupled receptors.Regulation of phosphatidylinositol-specific phospholipase C at the nuclear envelope in cardiac myocytes.Metabotropic glutamate receptor subtype 5: molecular pharmacology, allosteric modulation and stimulus biasNuclear Phosphatidylinositol Signaling: Focus on Phosphatidylinositol Phosphate Kinases and Phospholipases C.Sequences within the C Terminus of the Metabotropic Glutamate Receptor 5 (mGluR5) Are Responsible for Inner Nuclear Membrane Localization.Cardiac inositol 1,4,5-trisphosphate receptors.Effects of positive allosteric modulators on single-cell oscillatory Ca2+ signaling initiated by the type 5 metabotropic glutamate receptor.Biased allosteric agonism and modulation of metabotropic glutamate receptor 5: Implications for optimizing preclinical neuroscience drug discovery.GPCR signalling from within the cell.
P2860
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P2860
Activated nuclear metabotropic glutamate receptor mGlu5 couples to nuclear Gq/11 proteins to generate inositol 1,4,5-trisphosphate-mediated nuclear Ca2+ release.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Activated nuclear metabotropic ...... mediated nuclear Ca2+ release.
@en
type
label
Activated nuclear metabotropic ...... mediated nuclear Ca2+ release.
@en
prefLabel
Activated nuclear metabotropic ...... mediated nuclear Ca2+ release.
@en
P2093
P2860
P356
P1476
Activated nuclear metabotropic ...... mediated nuclear Ca2+ release.
@en
P2093
Karen L O'Malley
Vikas Kumar
Yuh-Jiin I Jong
P2860
P304
14072-14083
P356
10.1074/JBC.M708551200
P407
P577
2008-03-12T00:00:00Z