Initiation of V(D)J recombination in a cell-free system.
about
Base flipping in tn10 transposition: an active flip and capture mechanismV(D)J recombination and the evolution of the adaptive immune systemAmino acid residues in RAG1 responsible for the interaction with RAG2 during the V(D)J recombination processV(D)J recombination: modulation of RAG1 and RAG2 cleavage activity on 12/23 substrates by whole cell extract and DNA-bending proteinsThe RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2Lack of MSH2 involvement differentiates V(D)J recombination from other non-homologous end joining eventsKu70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombinationThe XRCC4 gene product is a target for and interacts with the DNA-dependent protein kinaseMechanistic constraints on diversity in human V(D)J recombinationMolluscan mobile elements similar to the vertebrate Recombination-Activating GenesCloning and functional characterization of the early-lymphocyte-specific Pb99 geneAutoubiquitylation of the V(D)J recombinase protein RAG1hBRAG, a novel B cell lineage cDNA encoding a type II transmembrane glycoprotein potentially involved in the regulation of recombination activating gene 1 (RAG1).Feline T-Cell Receptor gamma V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats.DNA hairpin opening mediated by the RAG1 and RAG2 proteins.The origins of the Rag genes--from transposition to V(D)J recombination.Equine severe combined immunodeficiency: a defect in V(D)J recombination and DNA-dependent protein kinase activity.Nonhomologous DNA end joining in cell-free systems.Distinct roles of RAG1 and RAG2 in binding the V(D)J recombination signal sequences.Functional analysis of coordinated cleavage in V(D)J recombination.Failure of hairpin-ended and nicked DNA To activate DNA-dependent protein kinase: implications for V(D)J recombinationNucleotide pool imbalance and adenosine deaminase deficiency induce alterations of N-region insertions during V(D)J recombination.Genetic pathway to recurrent chromosome translocations in murine lymphoma involves V(D)J recombinase.Differential requirements for cis and trans V(D)J cleavage: effects of substrate lengthInitiation of V(D)J recombination in vivo: role of recombination signal sequences in formation of single and paired double-strand breaks.Stimulation of V(D)J cleavage by high mobility group proteins.Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks.Transcription factors E2A, FOXO1 and FOXP1 regulate recombination activating gene expression in cancer cells.RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex.Detection of RAG protein-V(D)J recombination signal interactions near the site of DNA cleavage by UV cross-linking.A RAG1 and RAG2 tetramer complex is active in cleavage in V(D)J recombination.Mutations in conserved regions of the predicted RAG2 kelch repeats block initiation of V(D)J recombination and result in primary immunodeficienciesThe DDE motif in RAG-1 is contributed in trans to a single active site that catalyzes the nicking and transesterification steps of V(D)J recombinationConditional RAG-1 mutants block the hairpin formation step of V(D)J recombination.A C-terminal region of RAG1 contacts the coding DNA during V(D)J recombination.Rag-1 mutations associated with B-cell-negative scid dissociate the nicking and transesterification steps of V(D)J recombination.RAG transposase can capture and commit to target DNA before or after donor cleavageFootprint analysis of the RAG protein recombination signal sequence complex for V(D)J type recombination.Ordered assembly of the V(D)J synaptic complex ensures accurate recombinationDNA recombination as a possible mechanism in declarative memory: a hypothesis.
P2860
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P2860
Initiation of V(D)J recombination in a cell-free system.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Initiation of V(D)J recombination in a cell-free system.
@en
type
label
Initiation of V(D)J recombination in a cell-free system.
@en
prefLabel
Initiation of V(D)J recombination in a cell-free system.
@en
P2093
P1433
P1476
Initiation of V(D)J recombination in a cell-free system
@en
P2093
D A Ramsden
D C van Gent
J F McBlane
P304
P356
10.1016/0092-8674(95)90012-8
P407
P577
1995-06-01T00:00:00Z