Structural requirement of the calcium-channel subunit alpha2delta for gabapentin binding.
about
Mutation in the auxiliary calcium-channel subunit CACNA2D4 causes autosomal recessive cone dystrophyGabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesisCACNA2D2-mediated apoptosis in NSCLC cells is associated with alterations of the intracellular calcium signaling and disruption of mitochondria membrane integrityNew molecular targets for antiepileptic drugs: alpha(2)delta, SV2A, and K(v)7/KCNQ/M potassium channelsPharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentinThe Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic PotentialStructure-function of proteins interacting with the α1 pore-forming subunit of high-voltage-activated calcium channelsThe neurobiology of antiepileptic drugsFunctional exofacially tagged N-type calcium channels elucidate the interaction with auxiliary α2δ-1 subunits.Identification of the alpha2-delta-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin.New Horizons in the development of antiepileptic drugs: Innovative strategies.Amperometric measurement of glutamate release modulation by gabapentin and pregabalin in rat neocortical slices: role of voltage-sensitive Ca2+ α2δ-1 subunitTranscriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity.Weighing the balance: how analgesics used in chronic pain influence sleep?Pilot trial of gabapentin for the treatment of benzodiazepine abuse or dependence in methadone maintenance patients.Differential upregulation in DRG neurons of an α2δ-1 splice variant with a lower affinity for gabapentin after peripheral sensory nerve injury.The calcium channel alpha2/delta1 subunit is involved in extracellular signalling.α2δ expression sets presynaptic calcium channel abundance and release probabilityInhibition of neuronal Ca(2+) influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices.Pregabalin reduces cocaine self-administration and relapse to cocaine seeking in the rat.Pregabalin reduces alcohol drinking and relapse to alcohol seeking in the rat.The α2δ-1-NMDA Receptor Complex Is Critically Involved in Neuropathic Pain Development and Gabapentin Therapeutic Actions.
P2860
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P2860
Structural requirement of the calcium-channel subunit alpha2delta for gabapentin binding.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Structural requirement of the calcium-channel subunit alpha2delta for gabapentin binding.
@en
type
label
Structural requirement of the calcium-channel subunit alpha2delta for gabapentin binding.
@en
prefLabel
Structural requirement of the calcium-channel subunit alpha2delta for gabapentin binding.
@en
P2093
P2860
P1433
P1476
Structural requirement of the calcium-channel subunit alpha2delta for gabapentin binding.
@en
P2093
P2860
P304
P356
10.1042/0264-6021:3420313
P407
P478
342 ( Pt 2)
P577
1999-09-01T00:00:00Z