about
GNAO1 encephalopathy: further delineation of a severe neurodevelopmental syndrome affecting females.Characterization of the calcium-mediated response to alkaline stress in Saccharomyces cerevisiae.Agonist induction, conformational selection, and mutant receptorsRole of elastin in spontaneously hypertensive rat small mesenteric artery remodellingIncreased superoxide anion production by interleukin-1beta impairs nitric oxide-mediated relaxation in resistance arteriesLabel noise in subtype discrimination of class C G protein-coupled receptors: A systematic approach to the analysis of classification errors.On the fitting of binding data when receptor dimerization is suspected.Assessing the (a)symmetry of concentration-effect curves: empirical versus mechanistic models.Chromosomal bands affected by acute oil exposure and DNA repair errors.Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism.Follow-Up Genotoxic Study: Chromosome Damage Two and Six Years after Exposure to the Prestige Oil Spill.Persistence of Breakage in Specific Chromosome Bands 6 Years after Acute Exposure to Oil.Assessing receptor affinity for inverse agonists: Schild and Cheng-Prusoff methods revisited.The asymmetric/symmetric activation of GPCR dimers as a possible mechanistic rationale for multiple signalling pathways.Modeling cooperativity effects in dimeric G protein-coupled receptors.Mechanistic analysis of the function of agonists and allosteric modulators: reconciling two-state and operational models.Mathematical modeling of G protein-coupled receptor function: what can we learn from empirical and mechanistic models?Conformational analysis of GpA and GpAp in aqueous solution by molecular dynamics and statistical methods.Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer.A genomewide screen for tolerance to cationic drugs reveals genes important for potassium homeostasis in Saccharomyces cerevisiae.Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells.Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulatorComputational analysis of negative and positive allosteric modulator binding and function in metabotropic glutamate receptor 5 (in)activation.Integrated synthetic, pharmacological, and computational investigation of cis-2-(3,5-dichlorophenylcarbamoyl)cyclohexanecarboxylic acid enantiomers as positive allosteric modulators of metabotropic glutamate receptor subtype 4.Have many estimates of efficacy and affinity been misled? Revisiting the operational model of agonism.Paternal Age and Numerical Chromosome Abnormalities in Human Spermatozoa.Evidence for distinct antagonist-revealed functional states of 5-hydroxytryptamine(2A) receptor homodimers.Head circumference growth function as a marker of neurological impairment in a cohort of microcephalic infants and children.The effect of the molecular mechanism of G protein-coupled receptor activation on the process of signal transduction.An allosteric modulator to control endogenous G protein-coupled receptors with light.How inverse can a neutral antagonist be? Strategic questions after the rimonabant issue.Alpha 1-adrenoceptor vasoconstriction in the tail artery during ageing.Adrenergic and purinergic components in bisected vas deferens from spontaneously hypertensive rats.Enhanced noradrenergic transmission in the spontaneously hypertensive rat anococcygeus muscle.Ecophysiological significance of scale-dependent patterns in prokaryotic genomes unveiled by a combination of statistic and genometric analyses.Changes in electrophysiological properties in the prostatic portion of vas deferens from spontaneously hypertensive rats.Shift in nucleotide conformational equilibrium contributes to increased rate of catalysis of GpAp versus GpA in barnase.The influence of alignment-free sequence representations on the semi-supervised classification of class C G protein-coupled receptors: semi-supervised classification of class C GPCRs.Multiple active receptor conformation, agonist efficacy and maximum effect of the system: the conformation-based operational model of agonism.Coupling of the guanosine glycosidic bond conformation and the ribonucleotide cleavage reaction: implications for barnase catalysis.
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description
hulumtues
@sq
onderzoeker
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researcher
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ricercatore
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հետազոտող
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name
Jesús Giraldo
@ast
Jesús Giraldo
@en
Jesús Giraldo
@es
Jesús Giraldo
@sl
type
label
Jesús Giraldo
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Jesús Giraldo
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Jesús Giraldo
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Jesús Giraldo
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prefLabel
Jesús Giraldo
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Jesús Giraldo
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Jesús Giraldo
@es
Jesús Giraldo
@sl
P214
P244
P950
P1053
F-9881-2011
P106
P1580
P21
P213
0000 0001 4018 2126
P214
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nb2011027688
P31
P3829
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0000-0001-7082-4695
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osd2014849677
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lccn-nb2011027688