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Apolipoprotein A-I directly interacts with amyloid precursor protein and inhibits A beta aggregation and toxicityCysteine 73 in bleomycin hydrolase is critical for amyloid precursor protein processingHuman bleomycin hydrolase binds ribosomal proteinsEssential binding and functional domains of human bleomycin hydrolaseThe liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimer's diseaseOpposing effects of Apoe/Apoa1 double deletion on amyloid-β pathology and cognitive performance in APP mice.Anti-Amyloid Effects of Small Molecule Aβ-Binding Agents in PS1/APP MiceApolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 miceGenome-wide alteration of histone H3K9 acetylation pattern in mouse offspring prenatally exposed to arsenicRNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment.Bexarotene-Activated Retinoid X Receptors Regulate Neuronal Differentiation and Dendritic Complexity.RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers.Role of LXR and ABCA1 in the pathogenesis of Alzheimer's disease - implications for a new therapeutic approach.The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegenerationGenome-wide approaches reveal EGR1-controlled regulatory networks associated with neurodegeneration.ATP-binding cassette transporter A1: from metabolism to neurodegeneration.Proton pump inhibitor lansoprazole is a nuclear liver X receptor agonist.22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion.Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice.Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-beta in Alzheimer's disease brain but not in transgenic mouse brain.Metabolic Disorders and Neurodegeneration, introduction to the special issue.The C-terminus of human bleomycin hydrolase is required for protection against bleomycin-induced chromosomal damageSchedule dependent variation in human lymphocyte sensitivity to bleomycin and repair of chromosomal aberrations in G2Synergistic effect of CCNU and bleomycin on human lymphocytes exposed at late G1 and G2 states of the cell cycleABCA1 haplodeficiency affects the brain transcriptome following traumatic brain injury in mice expressing human APOE isoformsTherapeutic targeting of nuclear receptors, liver X and retinoid X receptors, for Alzheimer's disease
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description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Radosveta Koldamova
@ast
Radosveta Koldamova
@en
Radosveta Koldamova
@es
Radosveta Koldamova
@sl
type
label
Radosveta Koldamova
@ast
Radosveta Koldamova
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Radosveta Koldamova
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Radosveta Koldamova
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prefLabel
Radosveta Koldamova
@ast
Radosveta Koldamova
@en
Radosveta Koldamova
@es
Radosveta Koldamova
@sl
P106
P1153
6602241148
P21
P31
P496
0000-0002-6761-0984