Deubiquitinases and the new therapeutic opportunities offered to cancer.
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The quest for an effective and safe personalized cell therapy using epigenetic toolsDeubiquitinases (DUBs) and DUB inhibitors: a patent reviewUSP22 knockdown enhanced chemosensitivity of hepatocellular carcinoma cells to 5-Fu by up-regulation of Smad4 and suppression of Akt.Prognostic relevance of UCH-L1 and α-internexin in pancreatic neuroendocrine tumors.Loss of nuclear BAP1 expression is associated with poor prognosis in oral mucosal melanomaThe combined effect of USP7 inhibitors and PARP inhibitors in hormone-sensitive and castration-resistant prostate cancer cells.USP22 maintains gastric cancer stem cell stemness and promotes gastric cancer progression by stabilizing BMI1 proteinPlatinum-containing compound platinum pyrithione suppresses ovarian tumor proliferation through proteasome inhibitionDeubiquitinase OTUD6B Isoforms Are Important Regulators of Growth and Proliferation.Two clinical drugs deubiquitinase inhibitor auranofin and aldehyde dehydrogenase inhibitor disulfiram trigger synergistic anti-tumor effects in vitro and in vivo.HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma.Interplay of Toll-Like Receptor 9, Myeloid Cells, and Deubiquitinase A20 in Periodontal Inflammation.miR-130b, an onco-miRNA in bladder cancer, is directly regulated by NF-κB and sustains NF-κB activation by decreasing Cylindromatosis expression.Chemical and semisynthetic approaches to study and target deubiquitinases.The role of fulvestrant in endometrial cancer.A Review on Ubiquitination of Neurotrophin Receptors: Facts and Perspectives.Protein deubiquitinase USP7 is required for osteogenic differentiation of human adipose-derived stem cells.Uncovering the role of USP54 in cancer.Molecular mechanism for the substrate recognition of USP7.Ubiquitin C-terminal hydrolase isozyme L1 is associated with shelterin complex at interstitial telomeric sites.Hypoxia induces epithelial-mesenchymal transition in colorectal cancer cells through ubiquitin-specific protease 47-mediated stabilization of Snail: A potential role of Sox9.Evidence for the ISG15-Specific Deubiquitinase USP18 as an Antineoplastic Target.Deubiquitinating enzyme USP22 positively regulates c-Myc stability and tumorigenic activity in mammalian and breast cancer cells.Trip12 is an E3 ubiquitin ligase for USP7/HAUSP involved in the DNA damage response.Aberrant Low Expression of A20 in Tumor Necrosis Factor-α-stimulated SLE Monocytes Mediates Sustained NF-κB Inflammatory Response.FAM188B enhances cell survival via interaction with USP7.Inhibition of Ubiquitin-Specific Proteases as a Novel Anticancer Therapeutic StrategyInhibiting Multiple Deubiquitinases to Reduce Androgen Receptor Expression in Prostate Cancer CellsIdentification and Characterization of USP7 Targets in Cancer Cells
P2860
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P2860
Deubiquitinases and the new therapeutic opportunities offered to cancer.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
@wuu
2015年学术文章
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2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
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2015年學術文章
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2015年學術文章
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2015年學術文章
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name
Deubiquitinases and the new therapeutic opportunities offered to cancer.
@en
type
label
Deubiquitinases and the new therapeutic opportunities offered to cancer.
@en
prefLabel
Deubiquitinases and the new therapeutic opportunities offered to cancer.
@en
P2093
P2860
P921
P356
P1476
Deubiquitinases and the new therapeutic opportunities offered to cancer.
@en
P2093
Ira Kay Lacdao
Roland Pfoh
Vivian Saridakis
P2860
P304
P356
10.1530/ERC-14-0516
P5008
P577
2015-02-01T00:00:00Z