RNA binding activity of heterodimeric splicing factor U2AF: at least one RS domain is required for high-affinity binding.
about
Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF(65)Interaction between subunits of heterodimeric splicing factor U2AF is essential in vivo.The role of U2AF35 and U2AF65 in enhancer-dependent splicingU2AF homology motifs: protein recognition in the RRM worldDeletion of the N-terminus of SF2/ASF permits RS-domain-independent pre-mRNA splicing.Analysis of mutant phenotypes and splicing defects demonstrates functional collaboration between the large and small subunits of the essential splicing factor U2AF in vivo.Molecular genetic analysis of U2AF59 in Schizosaccharomyces pombe: differential sensitivity of introns to mutational inactivation.U2AF35 is encoded by an essential gene clustered in an operon with RRM/cyclophilin in Caenorhabditis elegans.RNA structure replaces the need for U2AF2 in splicing.RNA-protein interactions that regulate pre-mRNA splicing.The Drosophila U1-70K protein is required for viability, but its arginine-rich domain is dispensable.ATM and ATR pathways signal alternative splicing of Drosophila TAF1 pre-mRNA in response to DNA damage.U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicingA conditional role of U2AF in splicing of introns with unconventional polypyrimidine tractsAn exon that prevents transport of a mature mRNA.Functioning of the Drosophila Wilms'-tumor-1-associated protein homolog, Fl(2)d, in Sex-lethal-dependent alternative splicingGenomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutationsThe splicing factor U2AF small subunit is functionally conserved between fission yeast and humans.In vivo requirement of the small subunit of U2AF for recognition of a weak 3' splice site.Evidence for substrate-specific requirement of the splicing factor U2AF(35) and for its function after polypyrimidine tract recognition by U2AF(65).Evolution of a tissue-specific splicing network.A novel 3' splice site recognition by the two zinc fingers in the U2AF small subunit.Structuring of the 3' splice site by U2AF65.Both subunits of U2AF recognize the 3' splice site in Caenorhabditis elegans.
P2860
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P2860
RNA binding activity of heterodimeric splicing factor U2AF: at least one RS domain is required for high-affinity binding.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
RNA binding activity of hetero ...... red for high-affinity binding.
@en
type
label
RNA binding activity of hetero ...... red for high-affinity binding.
@en
prefLabel
RNA binding activity of hetero ...... red for high-affinity binding.
@en
P2093
P2860
P356
P1476
RNA binding activity of hetero ...... red for high-affinity binding.
@en
P2093
P2860
P304
P356
10.1128/MCB.18.7.4004
P407
P577
1998-07-01T00:00:00Z