Conserved nucleotides within the J domain of the encephalomyocarditis virus internal ribosome entry site are required for activity and for interaction with eIF4G.
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Insights into the Biology of IRES Elements through Riboproteomic ApproachesNMR studies of the structure and Mg2+ binding properties of a conserved RNA motif of EMCV picornavirus IRES elementSARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavageTranslation initiation mediated by RNA looping.Common conformational changes induced in type 2 picornavirus IRESs by cognate trans-acting factors.A distinct class of internal ribosomal entry site in members of the Kobuvirus and proposed Salivirus and Paraturdivirus genera of the Picornaviridae.Magnesium-dependent folding of a picornavirus IRES element modulates RNA conformation and eIF4G interaction.The mechanism of translation initiation on Aichivirus RNA mediated by a novel type of picornavirus IRES.Cap-dependent translation is mediated by 'RNA looping' rather than 'ribosome scanning'.An accurately preorganized IRES RNA structure enables eIF4G capture for initiation of viral translation.Local RNA flexibility perturbation of the IRES element induced by a novel ligand inhibits viral RNA translation.Evidence for an RNA chaperone function of polypyrimidine tract-binding protein in picornavirus translationRaman and Raman optical activity (ROA) analysis of RNA structural motifs in Domain I of the EMCV IRES.Evidence of reciprocal tertiary interactions between conserved motifs involved in organizing RNA structure essential for internal initiation of translation.In silico analysis of IRES RNAs of foot-and-mouth disease virus and related picornaviruses.Evolutionary conserved motifs constrain the RNA structure organization of picornavirus IRES.Insights into Structural and Mechanistic Features of Viral IRES Elements.
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P2860
Conserved nucleotides within the J domain of the encephalomyocarditis virus internal ribosome entry site are required for activity and for interaction with eIF4G.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Conserved nucleotides within t ...... nd for interaction with eIF4G.
@en
type
label
Conserved nucleotides within t ...... nd for interaction with eIF4G.
@en
prefLabel
Conserved nucleotides within t ...... nd for interaction with eIF4G.
@en
P2860
P1433
P1476
Conserved nucleotides within t ...... and for interaction with eIF4G
@en
P2093
Angela T Clark
Morwenna E M Robertson
P2860
P304
12441-12449
P356
10.1128/JVI.77.23.12441-12449.2003
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P577
2003-12-01T00:00:00Z