The N-terminal domain of the murine coronavirus spike glycoprotein determines the CEACAM1 receptor specificity of the virus strain.
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Acquisition of cell-cell fusion activity by amino acid substitutions in spike protein determines the infectivity of a coronavirus in cultured cellsPathogenesis of Afa/Dr diffusely adhering Escherichia coli.Structure, Function, and Evolution of Coronavirus Spike Proteins.Recombinant mouse hepatitis virus strain A59 from cloned, full-length cDNA replicates to high titers in vitro and is fully pathogenic in vivoMurine coronavirus evolution in vivo: functional compensation of a detrimental amino acid substitution in the receptor binding domain of the spike glycoprotein.Pathogenesis of murine coronavirus in the central nervous system.Murine coronavirus receptors are differentially expressed in the central nervous system and play virus strain-dependent roles in neuronal spreadBoth spike and background genes contribute to murine coronavirus neurovirulenceMurine coronavirus-induced hepatitis: JHM genetic background eliminates A59 spike-determined hepatotropismAntigenic modules in the N-terminal S1 region of the transmissible gastroenteritis virus spike proteinAmino acid substitutions in the S2 subunit of mouse hepatitis virus variant V51 encode determinants of host range expansionEnhanced virulence mediated by the murine coronavirus, mouse hepatitis virus strain JHM, is associated with a glycine at residue 310 of the spike glycoprotein.Proteolytic activation of the spike protein at a novel RRRR/S motif is implicated in furin-dependent entry, syncytium formation, and infectivity of coronavirus infectious bronchitis virus in cultured cellsAmino acids 270 to 510 of the severe acute respiratory syndrome coronavirus spike protein are required for interaction with receptor.Ceacam1a-/- mice are completely resistant to infection by murine coronavirus mouse hepatitis virus A59.Murine coronavirus neuropathogenesis: determinants of virulence.Cooperative involvement of the S1 and S2 subunits of the murine coronavirus spike protein in receptor binding and extended host range.Murine coronavirus with an extended host range uses heparan sulfate as an entry receptor.Conformational changes in the spike glycoprotein of murine coronavirus are induced at 37 degrees C either by soluble murine CEACAM1 receptors or by pH 8.Identification of a receptor-binding domain of the spike glycoprotein of human coronavirus HCoV-229E.The N-terminal region of the murine coronavirus spike glycoprotein is associated with the extended host range of viruses from persistently infected murine cells.Redirecting coronavirus to a nonnative receptor through a virus-encoded targeting adapter.SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells.Mosaic evolution of the severe acute respiratory syndrome coronavirus.Luxury at a cost? Recombinant mouse hepatitis viruses expressing the accessory hemagglutinin esterase protein display reduced fitness in vitro.Soluble receptor-mediated targeting of mouse hepatitis coronavirus to the human epidermal growth factor receptor.Pathogenesis of neurotropic murine coronavirus is multifactorial.
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P2860
The N-terminal domain of the murine coronavirus spike glycoprotein determines the CEACAM1 receptor specificity of the virus strain.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
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2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
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2003年學術文章
@zh-hant
name
The N-terminal domain of the m ...... ecificity of the virus strain.
@en
type
label
The N-terminal domain of the m ...... ecificity of the virus strain.
@en
prefLabel
The N-terminal domain of the m ...... ecificity of the virus strain.
@en
P2860
P1433
P1476
The N-terminal domain of the m ...... ecificity of the virus strain.
@en
P2093
Bruce D Zelus
Jean C Tsai
P2860
P304
P356
10.1128/JVI.77.2.841-850.2003
P407
P577
2003-01-01T00:00:00Z