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Recent advances in combinatorial biosynthesis for drug discovery

Recent advances in combinatorial biosynthesis for drug discovery

http://www.wikidata.org/entity/Q38364681

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Accessing Nature's diversity through metabolic engineering and synthetic biology Synthetic biology for pharmaceutical drug discovery Rational and combinatorial tailoring of bioactive cyclic dipeptides Precursor-Directed Combinatorial Biosynthesis of Cinnamoyl, Dihydrocinnamoyl, and Benzoyl Anthranilates in Saccharomyces cerevisiae Exploiting members of the BAHD acyltransferase family to synthesize multiple hydroxycinnamate and benzoate conjugates in yeast.Marine Rare Actinobacteria: Isolation, Characterization, and Strategies for Harnessing Bioactive Compounds.Commentary: Toward a new focus in antibiotic and drug discovery from the Streptomyces arsenal Engineering microbial hosts for production of bacterial natural products Identification of a Thioesterase Bottleneck in the Pikromycin Pathway through Full-Module Processing of Unnatural Pentaketides.A plug-and-play pathway refactoring workflow for natural product research in Escherichia coli and Saccharomyces cerevisiae.Precursor-directed combinatorial biosynthesis of cephalosporin analogue by endolithic actinobacterium Streptomyces sp. AL51 by utilizing thiophene derivative.Synthetic biology approaches and combinatorial biosynthesis towards heterologous lipopeptide production

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Recent advances in combinatorial biosynthesis for drug discovery

http://www.wikidata.org/entity/Q38364681

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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2015年學術文章

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2015年學術文章

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Recent advances in combinatorial biosynthesis for drug discovery

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Recent advances in combinatorial biosynthesis for drug discovery

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Drug Design, Development and Therapy

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Recent advances in combinatorial biosynthesis for drug discovery

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Ee Lui Ang

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Huimin Zhao

http://www.w3.org/2001/XMLSchema#string

Zihe Liu

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Creative Commons Attribution-NonCommercial

P2860

Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling

Structural basis for the one-pot formation of the diarylheptanoid scaffold by curcuminoid synthase from Oryza sativa

Synthesis of unnatural alkaloid scaffolds by exploiting plant polyketide synthase

Sequencing technologies - the next generation

Real-time DNA sequencing from single polymerase molecules

How to improve R&D productivity: the pharmaceutical industry's grand challenge

Characterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreus

High-throughput screening for industrial enzyme production hosts by droplet microfluidics.

Combinatorial biosynthesis of polyketides--a perspective.

Combinatorial biosynthesis of sapogenins and saponins in Saccharomyces cerevisiae using a C-16α hydroxylase from Bupleurum falcatum.

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823-833

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10.2147/DDDT.S63023

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biomedical investigative technique

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