Evolutionary consequences of drug resistance: shared principles across diverse targets and organisms.
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Pharmacogenomics in the clinicApproved Antiviral Drugs over the Past 50 YearsEvolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole PhysiologyTime-programmable drug dosing allows the manipulation, suppression and reversal of antibiotic drug resistance in vitroAnti-infective Activity of 2-Cyano-3-Acrylamide Inhibitors with Improved Drug-Like Properties against Two Intracellular Pathogens.How to Use a Chemotherapeutic Agent When Resistance to It Threatens the Patient.Within-Host Selection of Drug Resistance in a Mouse Model Reveals Dose-Dependent Selection of Atovaquone Resistance MutationsMultidrug-resistant bacteria compensate for the epistasis between resistances.Combinatorial Genetic Modeling of pfcrt-Mediated Drug Resistance Evolution in Plasmodium falciparum.Compensating the Fitness Costs of Synonymous Mutations.Complex Interplay of Physiology and Selection in the Emergence of Antibiotic Resistance.Improving Viral Protease Inhibitors to Counter Drug Resistance.Putative RNA-Directed Adaptive Mutations in Cancer Evolution.High-Definition Medicine.Prediction of antibiotic resistance: time for a new preclinical paradigm?Stress management by autophagy: Implications for chemoresistance.Biased small-molecule ligands for selective inhibition of HIV-1 cell entry via CCR5.New facets of antifungal therapy.Evolving lessons on nanomaterial-coated viral vectors for local and systemic gene therapy.Resistance and cross-resistance profile of the diaryltriazine NNRTI and candidate microbicide UAMC01398.Evolutionary scalpels for dissecting tumor ecosystems.Epistasis and the Evolution of Antimicrobial Resistance.Novel Pathways for Ameliorating the Fitness Cost of Gentamicin Resistant Small Colony Variants.Genomic evolution of bacterial populations under coselection by antibiotics and phage.Are RNA Viruses Candidate Agents for the Next Global Pandemic? A Review.Single-virion sequencing of lamivudine-treated HBV populations reveal population evolution dynamics and demographic historyThe structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion.Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics.Automated growth rate determination in high-throughput microbioreactor systems.Initial non-operative management of uncomplicated appendicitis in children: a protocol for a multicentre randomised controlled trial (APAC trial).Artificial Gene Amplification in Escherichia coli Reveals Numerous Determinants for Resistance to Metal Toxicity.Fitness tradeoffs of antibiotic resistance in extra-intestinal pathogenic Escherichia coli.Nothing in cancer makes sense except….The effects of subcurative praziquantel treatment on life-history traits and trade-offs in drug-resistant Schistosoma mansoni.The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa.Predicting evolution.Directed evolution of multiple genomic loci allows the prediction of antibiotic resistance.Insights into the processes that drive the evolution of drug resistance in Mycobacterium tuberculosisManaging the emergence of pathogen resistance via spatially targeted antimicrobial use
P2860
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P2860
Evolutionary consequences of drug resistance: shared principles across diverse targets and organisms.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Evolutionary consequences of d ...... diverse targets and organisms.
@en
type
label
Evolutionary consequences of d ...... diverse targets and organisms.
@en
prefLabel
Evolutionary consequences of d ...... diverse targets and organisms.
@en
P2860
P356
P1476
Evolutionary consequences of d ...... diverse targets and organisms.
@en
P2093
Dan I Andersson
P2860
P2888
P304
P356
10.1038/NRG3922
P577
2015-07-07T00:00:00Z
P6179
1013069915