Genetic engineering of modular PKSs: from combinatorial biosynthesis to synthetic biology.
about
Discovery Strategies of Bioactive Compounds Synthesized by Nonribosomal Peptide Synthetases and Type-I Polyketide Synthases Derived from Marine Microbiomes.Using natural products for drug discovery: the impact of the genomics era.Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substratePolyketide stereocontrol: a study in chemical biology.Towards Precision Engineering of Canonical Polyketide Synthase Domains: Recent Advances and Future Prospects.A Protein Interaction Map of the Kalimantacin Biosynthesis Assembly LineMetabolic engineering with systems biology tools to optimize production of prokaryotic secondary metabolites.An overview of rapamycin: from discovery to future perspectives.Mining Bacterial Genomes for Secondary Metabolite Gene Clusters.Chimeric Leader Peptides for the Generation of Non-Natural Hybrid RiPP Products.Synthetic biology of modular proteins.A Single Active Site Mutation in the Pikromycin Thioesterase Generates a More Effective Macrocyclization Catalyst.Engineering modular polyketide synthases for production of biofuels and industrial chemicals.Biological characterization of the hygrobafilomycin antibiotic JBIR-100 and bioinformatic insights into the hygrolide family of natural products.Diversity oriented biosynthesis via accelerated evolution of modular gene clusters.Identification of a Thioesterase Bottleneck in the Pikromycin Pathway through Full-Module Processing of Unnatural Pentaketides.Directing evolution: the next revolution in drug discovery?Insights into the Dual Activity of a Bifunctional Dehydratase-Cyclase Domain.Strategies to diversify natural products for drug discovery.Characterization of Giant Modular PKSs Provides Insight into Genetic Mechanism for Structural Diversification of Aminopolyol Polyketides.Broadening substrate specificity of a chain-extending ketosynthase through a single active-site mutation.Evolution inspired engineering of antibiotic biosynthesis enzymes.Fatty acid synthases: Re-engineering biofactories.RiPP antibiotics: biosynthesis and engineering potential.De novo Biosynthesis of "Non-Natural" Thaxtomin Phytotoxins.Synthetic biology approaches and combinatorial biosynthesis towards heterologous lipopeptide production
P2860
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P2860
Genetic engineering of modular PKSs: from combinatorial biosynthesis to synthetic biology.
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
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2015年论文
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name
Genetic engineering of modular ...... ynthesis to synthetic biology.
@en
type
label
Genetic engineering of modular ...... ynthesis to synthetic biology.
@en
prefLabel
Genetic engineering of modular ...... ynthesis to synthetic biology.
@en
P2860
P356
P1476
Genetic engineering of modular ...... ynthesis to synthetic biology.
@en
P2093
Kira J Weissman
P2860
P304
P356
10.1039/C5NP00109A
P577
2015-11-10T00:00:00Z