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Acid sphingomyelinase deficiency in Western diet-fed mice protects against adipocyte hypertrophy and diet-induced liver steatosis.Identification of novel biomarker candidates for the immunohistochemical diagnosis of cholangiocellular carcinoma.Proteomic differences between hepatocellular carcinoma and nontumorous liver tissue investigated by a combined gel-based and label-free quantitative proteomics study.BioInfra.Prot: A comprehensive proteomics workflow including data standardization, protein inference, expression analysis and data publication.Broad and potent antiviral activity of the NAE inhibitor MLN4924.Immunohistochemical Markers Distinguishing Cholangiocellular Carcinoma (CCC) from Pancreatic Ductal Adenocarcinoma (PDAC) Discovered by Proteomic Analysis of Microdissected CellsEukaryotic elongation factor 2 is a prognostic marker and its kinase a potential therapeutic target in HCC.Metal-mediated base pairs in nucleic acids with purine- and pyrimidine-derived nucleosides.Conformational change induced by metal-ion-binding to DNA containing the artificial 1,2,4-triazole nucleoside.Quantitative Secretome Analysis of Activated Jurkat Cells Using Click Chemistry-Based Enrichment of Secreted Glycoproteins.Proteome Analyses of Hepatocellular Carcinoma.Structurally related hydrazone-based metal complexes with different antitumor activities variably induce apoptotic cell death.Label-free Proteomic Analysis of Exosomes Derived from Inducible Hepatitis B Virus-Replicating HepAD38 Cell Line.One Sample, One Shot - Evaluation of sample preparation protocols for the mass spectrometric proteome analysis of human bile fluid without extensive fractionation.Identification of proteins that mediate the pro-viral functions of the interferon stimulated gene 15 in hepatitis C virus replication.Comparison of label-free and label-based strategies for proteome analysis of hepatoma cell lines.Hepatic expression of proteasome subunit alpha type-6 is upregulated during viral hepatitis and putatively regulates the expression of ISG15 ubiquitin-like modifier, a proviral host gene in hepatitis C virus infection.Identification of the Consistently Altered Metabolic Targets in Human Hepatocellular Carcinoma.Quantitative Tissue Proteomics Analysis Reveals Versican as Potential Biomarker for Early-Stage Hepatocellular Carcinoma.Distinct Escape Pathway by Hepatitis C Virus Genotype 1a from a Dominant CD8+ T Cell Response by Selection of Altered Epitope Processing.Analysis of disease-associated protein expression using quantitative proteomics—fibulin-5 is expressed in association with hepatic fibrosis.The Canonical Immediate Early 3 Gene Product pIE611 of Mouse Cytomegalovirus Is Dispensable for Viral Replication but Mediates Transcriptional and Posttranscriptional Regulation of Viral Gene ProductsDeciphering of the Human Interferon-Regulated Proteome by Mass Spectrometry-Based Quantitative Analysis Reveals Extent and Dynamics of Protein Induction and Repression.A metal-mediated base pair that discriminates between the canonical pyrimidine nucleobases.Silver(I)-mediated cytosine self-pairing is preferred over hoogsteen-type base pairs with the artificial nucleobase 1,3-dideaza-6-nitropurine.A structured proteomic approach identifies 14-3-3Sigma as a novel and reliable protein biomarker in panel based differential diagnostics of liver tumors.NHS-based Tandem Mass Tagging of Proteins at the Level of Whole Cells: A Critical Evaluation in Comparison to Conventional TMT-Labeling Approaches for Quantitative Proteome Analysis.Mixed guanine, adenine base quartets: possible roles of protons and metal ions in their stabilization.Allergy-Protective Arabinogalactan Modulates Human Dendritic Cells via C-Type Lectins and Inhibition of NF-κB.Silver(I)-mediated Hoogsteen-type base pairs.Quantitative proteome analysis reveals the correlation between endocytosis-associated proteins and hepatocellular carcinoma dedifferentiation.Tissue-based quantitative proteome analysis of human hepatocellular carcinoma using tandem mass tags.Systematic analysis of synergistic proteome modulations in a drug combination of cisplatin and MLN4924Proteome Analysis of a Hepatocyte-Specific BIRC5 (Survivin)-Knockout Mouse Model during Liver RegenerationA Family of Hydrazone-Based Nucleosides for Use in Metal-Mediated Base PairsEfficient Synthesis of 1-Deaza-6-methoxypurine-N9-β-2′-deoxyribonucleoside and Related DNA Building BlocksContiguous Metal-Mediated Base Pairs Comprising Two AgI IonsSilver(I) and Mercury(II) Complexes with 1-Methyl-1,2,4-triazole as Models for Metal-Mediated Base Pairs - Formation of Discrete Complexes in Solution vs. One- and Two-Dimensional Coordination Polymers in the Solid StateInteraction of Pt(II) and Pd(II) complexes of terpyridine with 1-methylazoles: A combined experimental and density functional studyLabel-Free Proteomic Analysis of Exosomes Secreted from THP-1-Derived Macrophages Treated with IFN-α Identifies Antiviral Proteins Enriched in Exosomes
P50
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Dominik A. Megger
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Dominik A. Megger
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Dominik A. Megger
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Dominik A. Megger
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Dominik A. Megger
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Dominik A. Megger
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Dominik A. Megger
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Dominik A. Megger
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Dominik A. Megger
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Dominik A. Megger
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Dominik A. Megger
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