Molecular basis and current strategies of therapeutic arginine depletion for cancer.
about
A novel and promising therapeutic approach for NSCLC: recombinant human arginase alone or combined with autophagy inhibitor.Arginine-Dual roles as an onconutrient and immunonutrient.Recovery of pan-genotypic and genotype-specific amino acid alterations in chronic hepatitis C after viral clearance: transition at the crossroad of metabolism and immunity.PEGylated arginine deiminase can modulate tumor immune microenvironment by affecting immune checkpoint expression, decreasing regulatory T cell accumulation and inducing tumor T cell infiltration.Arginine auxotrophic gene signature in paediatric sarcomas and brain tumours provides a viable target for arginine depletion therapies.The arginine metabolome in acute lymphoblastic leukemia can be targeted by the pegylated-recombinant arginase I BCT-100.Metabolic therapy with PEG-arginase induces a sustained complete remission in immunotherapy-resistant melanoma.Integrated omics and gene expression analysis identifies the loss of metabolite–metabolite correlations in small cell lung cancer.
P2860
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P2860
Molecular basis and current strategies of therapeutic arginine depletion for cancer.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Molecular basis and current strategies of therapeutic arginine depletion for cancer.
@en
type
label
Molecular basis and current strategies of therapeutic arginine depletion for cancer.
@en
prefLabel
Molecular basis and current strategies of therapeutic arginine depletion for cancer.
@en
P2860
P356
P1476
Molecular basis and current strategies of therapeutic arginine depletion for cancer
@en
P2093
Ashley Vardon
Carmela De Santo
P2860
P304
P356
10.1002/IJC.30051
P577
2016-04-15T00:00:00Z