about
Cell cycle-dependent formation of Cdc45-Claspin complexes in human cells is compromized by UV-mediated DNA damageThe yeast CDC9 gene encodes both a nuclear and a mitochondrial form of DNA ligase I.A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage responseDDK dependent regulation of TOP2A at centromeres revealed by a chemical genetics approachTransient inhibition of ATM kinase is sufficient to enhance cellular sensitivity to ionizing radiationLethal errors in checkpoint control--life without Chk1.DNA mediated chromatin pull-down for the study of chromatin replication.Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpointAnalysing the DNA damage and replication checkpoints in DT40 cells.Cdc7-dependent and -independent phosphorylation of Claspin in the induction of the DNA replication checkpointCharacterization of a Dual CDC7/CDK9 Inhibitor in Multiple Myeloma Cellular ModelsThe Deubiquitinase USP9X Maintains DNA Replication Fork Stability and DNA Damage Checkpoint Responses by Regulating CLASPIN during S-Phase.Hypoxic activation of ATR and the suppression of the initiation of DNA replication through cdc6 degradationChk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects.Chk1-dependent S-M checkpoint delay in vertebrate cells is linked to maintenance of viable replication structures.DNA Replication Dynamics and Cellular Responses to ATP Competitive CDC7 Kinase Inhibitors.Chk2 is required for optimal mitotic delay in response to irradiation-induced DNA damage incurred in G2 phase.CDC7 kinase promotes MRE11 fork processing, modulating fork speed and chromosomal breakage
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description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Michael D Rainey
@ast
Michael D Rainey
@en
Michael D Rainey
@es
Michael D Rainey
@sl
type
label
Michael D Rainey
@ast
Michael D Rainey
@en
Michael D Rainey
@es
Michael D Rainey
@sl
prefLabel
Michael D Rainey
@ast
Michael D Rainey
@en
Michael D Rainey
@es
Michael D Rainey
@sl
P108
P106
P21
P31
P496
0000-0001-9777-873X