Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy.
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The Role of Chemokines in Shaping the Balance Between CD4(+) T Cell Subsets and Its Therapeutic Implications in Autoimmune and Cancer DiseasesThe Dipeptidyl Peptidase Family, Prolyl Oligopeptidase, and Prolyl Carboxypeptidase in the Immune System and Inflammatory Disease, Including AtherosclerosisRegulation of Chemokine Activity - A Focus on the Role of Dipeptidyl Peptidase IV/CD26Immune Cell Regulatory Pathways Unexplored as Host-Directed Therapeutic Targets for Mycobacterium tuberculosis: An Opportunity to Apply Precision Medicine Innovations to Infectious DiseasesFacilitating T Cell Infiltration in Tumor Microenvironment Overcomes Resistance to PD-L1 BlockadeFirst-in-human phase 1 of YS110, a monoclonal antibody directed against CD26 in advanced CD26-expressing cancers.Induction of cathepsin B by the CXCR3 chemokines CXCL9 and CXCL10 in human breast cancer cellsImmune escape to PD-L1/PD-1 blockade: seven steps to success (or failure).Predicting DPP-IV inhibitors with machine learning approaches.Inhibition of DPP4 activity in humans establishes its in vivo role in CXCL10 post-translational modification: prospective placebo-controlled clinical studiesDPPIV promotes endometrial carcinoma cell proliferation, invasion and tumorigenesis.DPP4/CD26 overexpression in urothelial carcinoma confers an independent prognostic impact and correlates with intrinsic biological aggressiveness.Immunotherapy and tumor microenvironmentGlycosaminoglycans Regulate CXCR3 Ligands at Distinct Levels: Protection against Processing by Dipeptidyl Peptidase IV/CD26 and Interference with Receptor Signaling.CD26/dipeptidylpeptidase IV-chemokine interactions: double-edged regulation of inflammation and tumor biology.NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis.The pro-fibrotic role of dipeptidyl peptidase 4 in carbon tetrachloride-induced experimental liver injury.Polymicrobial sepsis impairs bystander recruitment of effector cells to infected skin despite optimal sensing and alarming function of skin resident memory CD8 T cells.Discovery and validation of a colorectal cancer classifier in a new blood test with improved performance for high-risk subjects.Unlocking tumor vascular barriers with CXCR3: Implications for cancer immunotherapy.Galectin-3 captures interferon-gamma in the tumor matrix reducing chemokine gradient production and T-cell tumor infiltration.CXCL9, CXCL10, CXCL11/CXCR3 axis for immune activation - A target for novel cancer therapy.Human CD26high T cells elicit tumor immunity against multiple malignancies via enhanced migration and persistence.Sodium glucose cotransporter 2 inhibitor canagliflozin attenuates liver cancer cell growth and angiogenic activity by inhibiting glucose uptake.DPP4, the Middle East Respiratory Syndrome Coronavirus Receptor, is Upregulated in Lungs of Smokers and Chronic Obstructive Pulmonary Disease Patients.Combined treatment with dipeptidyl peptidase-4 inhibitor (sitagliptin) and angiotensin-II type 1 receptor blocker (losartan) suppresses progression in a non-diabetic rat model of steatohepatitis.Overview of the Mechanisms that May Contribute to the Non-Redundant Activities of Interferon-Inducible CXC Chemokine Receptor 3 Ligands.Suppression of CD26 inhibits growth and metastasis of pancreatic cancer.Possible new therapeutic agents for malignant pleural mesothelioma: anti-CD26 monoclonal antibody and naftopidil.Response to comment on "NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis".Comment on "NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis".A guide to chemokines and their receptors.Interferon-Gamma at the Crossroads of Tumor Immune Surveillance or Evasion.Repositioning of Omarigliptin as a once-weekly intranasal Anti-parkinsonian Agent.Metformin exerts antitumor activity via induction of multiple death pathways in tumor cells and activation of a protective immune response.Systemic DPP4 activity is reduced during primary HIV-1 infection and is associated with intestinal RORC+ CD4+ cell levels: a surrogate marker candidate of HIV-induced intestinal damage.Intercellular Communication in Tumor Biology: A Role for Mitochondrial TransferDipeptidyl Peptidase-4 Is a Pro-Recovery Mediator During Acute Hepatotoxic Damage and Mirrors Severe Shifts in Kupffer Cells
P2860
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P2860
Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Dipeptidylpeptidase 4 inhibiti ...... or immunity and immunotherapy.
@en
type
label
Dipeptidylpeptidase 4 inhibiti ...... or immunity and immunotherapy.
@en
prefLabel
Dipeptidylpeptidase 4 inhibiti ...... or immunity and immunotherapy.
@en
P2093
P2860
P356
P1433
P1476
Dipeptidylpeptidase 4 inhibiti ...... or immunity and immunotherapy.
@en
P2093
Laurence Fiette
Matthew L Albert
Melissa E Laird
Molly A Ingersoll
Nader Yatim
Rosa Barreira da Silva
P2860
P304
P356
10.1038/NI.3201
P407
P577
2015-06-15T00:00:00Z