Endoplasmic reticulum stress and cell death in mTORC1-overactive cells is induced by nelfinavir and enhanced by chloroquine.
about
Mourning Dr. Alfred G. Knudson: the two-hit hypothesis, tumor suppressor genes, and the tuberous sclerosis complexThe HIV protease inhibitor, nelfinavir, as a novel therapeutic approach for the treatment of refractory pediatric leukemia.ER stress: Autophagy induction, inhibition and selection.Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings.Targeting protein homeostasis with nelfinavir/salinomycin dual therapy effectively induces death of mTORC1 hyperactive cells.Mifepristone increases mRNA translation rate, triggers the unfolded protein response, increases autophagic flux, and kills ovarian cancer cells in combination with proteasome or lysosome inhibitors.The HIV protease and PI3K/Akt inhibitor nelfinavir does not improve the curative effect of fractionated irradiation in PC-3 prostate cancer in vitro and in vivo.Pulsatilla Saponin D Inhibits Autophagic Flux and Synergistically Enhances the Anticancer Activity of Chemotherapeutic Agents Against HeLa Cells.
P2860
Q28070171-A357830E-92F8-49DD-BF50-7DC799948C43Q33714126-EC5C3BAE-9EA5-4CC5-A4A5-9C69D0FBBFD2Q36777229-7AFCDB0F-AD69-4FB3-93EC-8871A4408947Q36981226-BFF618FA-01E4-4002-B61C-489AF3D194C4Q41472073-04152CE4-6049-4801-9C34-876A00490077Q41914993-61ADF73E-E094-4132-99ED-D9444427E10FQ53596358-81797785-7C0E-4311-AE4D-979BD1AD64A2Q54224174-65398733-6FB0-4EE0-A0EC-5B02940C3FE6
P2860
Endoplasmic reticulum stress and cell death in mTORC1-overactive cells is induced by nelfinavir and enhanced by chloroquine.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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name
Endoplasmic reticulum stress a ...... r and enhanced by chloroquine.
@en
type
label
Endoplasmic reticulum stress a ...... r and enhanced by chloroquine.
@en
prefLabel
Endoplasmic reticulum stress a ...... r and enhanced by chloroquine.
@en
P2093
P2860
P50
P1433
P1476
Endoplasmic reticulum stress a ...... ir and enhanced by chloroquine
@en
P2093
D Mark Davies
David K Hunt
Julian R Sampson
Marie Wiltshire
Rachel J Errington
P2860
P304
P356
10.1016/J.MOLONC.2014.11.005
P577
2014-11-22T00:00:00Z