HIV-1 Nef and Vpu are functionally redundant broad-spectrum modulators of cell surface receptors, including tetraspanins.
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SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by NefHIV Genome-Wide Protein Associations: a Review of 30 Years of ResearchRemodeling of the Host Cell Plasma Membrane by HIV-1 Nef and Vpu: A Strategy to Ensure Viral Fitness and PersistenceVpu Protein: The Viroporin Encoded by HIV-1Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef.HIV-1 Vpu utilizes both cullin-RING ligase (CRL) dependent and independent mechanisms to downmodulate host proteins.DDX60L Is an Interferon-Stimulated Gene Product Restricting Hepatitis C Virus Replication in Cell Culture.Association with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with the Exocyst Complex.The Vpu-interacting Protein SGTA Regulates Expression of a Non-glycosylated Tetherin Species.Down-modulation of primate lentiviral receptors by Nef proteins of simian immunodeficiency virus (SIV) of chimpanzees (SIVcpz) and related SIVs: implication for the evolutionary event at the emergence of SIVcpz.Reconstructing the temporal progression of HIV-1 immune response pathways.Temporal proteomic analysis of HIV infection reveals remodelling of the host phosphoproteome by lentiviral Vif variantsA Highly Conserved Residue in HIV-1 Nef Alpha Helix 2 Modulates Protein Expression.The Antagonism of HIV-1 Nef to SERINC5 Particle Infectivity Restriction Involves the Counteraction of Virion-Associated Pools of the Restriction Factor.Comprehensive Cross-Clade Characterization of Antibody-Mediated Recognition, Complement-Mediated Lysis, and Cell-Mediated Cytotoxicity of HIV-1 Envelope-Specific Antibodies toward Eradication of the HIV-1 Reservoir.HIV-1 Vpu Downmodulates ICAM-1 Expression, Resulting in Decreased Killing of Infected CD4+ T Cells by NK CellsVarious plus unique: Viral protein U as a plurifunctional protein for HIV-1 replicationThe host-cell restriction factor SERINC5 restricts HIV-1 infectivity without altering the lipid composition and organization of viral particles.HIV-1 Nef sequesters MHC-I intracellularly by targeting early stages of endocytosis and recycling.The Potency of Nef-Mediated SERINC5 Antagonism Correlates with the Prevalence of Primate Lentiviruses in the Wild.HIV-1 Vpu Antagonizes CD317/Tetherin by Adaptor Protein-1-Mediated Exclusion from Virus Assembly SitesMARCH8 inhibits HIV-1 infection by reducing virion incorporation of envelope glycoproteins.HIV-1 Nef and Vpu Interfere with L-Selectin (CD62L) Cell Surface Expression To Inhibit Adhesion and Signaling in Infected CD4+ T Lymphocytes.Vpu is the main determinant for tetraspanin downregulation in HIV-1-infected cells.Rab3a-Bound CD63 Is Degraded and Rab3a-Free CD63 Is Incorporated into HIV-1 Particles.A Long Cytoplasmic Loop Governs the Sensitivity of the Anti-viral Host Protein SERINC5 to HIV-1 Nef.The HIV-1 accessory proteins Nef and Vpu downregulate total and cell surface CD28 in CD4+ T cells.Multiple Inhibitory Factors Act in the Late Phase of HIV-1 Replication: a Systematic Review of the Literature.Intrinsic properties and plasma membrane trafficking route of Src family kinase SH4 domains sensitive to retargeting by HIV-1 Nef.Large-Scale Arrayed Analysis of Protein Degradation Reveals Cellular Targets for HIV-1 Vpu.Tetraspanins, Another Piece in the HIV-1 Replication PuzzleIFITM proteins inhibit HIV-1 protein synthesis
P2860
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P2860
HIV-1 Nef and Vpu are functionally redundant broad-spectrum modulators of cell surface receptors, including tetraspanins.
description
2014 nî lūn-bûn
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
HIV-1 Nef and Vpu are function ...... ptors, including tetraspanins.
@en
type
label
HIV-1 Nef and Vpu are function ...... ptors, including tetraspanins.
@en
prefLabel
HIV-1 Nef and Vpu are function ...... ptors, including tetraspanins.
@en
P2093
P2860
P356
P1433
P1476
HIV-1 Nef and Vpu are function ...... ptors, including tetraspanins.
@en
P2093
Birthe Müller
Claudia Haller
François M Pujol
Joëlle V Fritz
Miguel Lamas-Murua
Oliver T Keppler
P2860
P304
14241-14257
P356
10.1128/JVI.02333-14
P407
P577
2014-10-01T00:00:00Z