p-21 activated kinase 4 promotes proliferation and survival of pancreatic cancer cells through AKT- and ERK-dependent activation of NF-κB pathway.
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Group II p21-activated kinases as therapeutic targets in gastrointestinal cancerDeciphering the link between PI3K and PAK: An opportunity to target key pathways in pancreatic cancer?Signaling, Regulation, and Specificity of the Type II p21-activated Kinasesp-21 activated kinase 4 (PAK4) maintains stem cell-like phenotypes in pancreatic cancer cells through activation of STAT3 signalingPAK4 interacts with p85 alpha: implications for pancreatic cancer cell migrationActivated-PAK4 predicts worse prognosis in breast cancer and promotes tumorigenesis through activation of PI3K/AKT signaling.Molecular Drivers of Pancreatic Cancer Pathogenesis: Looking Inward to Move Forward.P21-activated kinase 4 involves TSH induced papillary thyroid cancer cell proliferation.Gastrointestinal hormones/neurotransmitters and growth factors can activate P21 activated kinase 2 in pancreatic acinar cells by novel mechanismsp21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes.Centrosomal protein 55 activates NF-κB signalling and promotes pancreatic cancer cells aggressiveness.MicroRNA-345 induces apoptosis in pancreatic cancer cells through potentiation of caspase-dependent and -independent pathways.Size is an essential parameter in governing the UVB-protective efficacy of silver nanoparticles in human keratinocytesResistin and interleukin-6 exhibit racially-disparate expression in breast cancer patients, display molecular association and promote growth and aggressiveness of tumor cells through STAT3 activation.Development and Characterization of a Novel in vitro Progression Model for UVB-Induced Skin CarcinogenesisHistidine-rich calcium binding protein promotes growth of hepatocellular carcinoma in vitro and in vivo.MiR-744 increases tumorigenicity of pancreatic cancer by activating Wnt/β-catenin pathway.Inactivation of M2 AChR/NF-κB signaling axis reverses epithelial-mesenchymal transition (EMT) and suppresses migration and invasion in non-small cell lung cancer (NSCLC).Gemcitabine triggers angiogenesis-promoting molecular signals in pancreatic cancer cells: Therapeutic implications.RelB/NF-κB links cell cycle transition and apoptosis to endometrioid adenocarcinoma tumorigenesis.Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells.DUSP1 inhibits cell proliferation, metastasis and invasion and angiogenesis in gallbladder cancer.Tolfenamic acid-induced alterations in genes and pathways in pancreatic cancer cells.Potential therapeutic applications of plant toxin-ricin in cancer: challenges and advances.Pdx1-Cre-driven conditional gene depletion suggests PAK4 as dispensable for mouse pancreas development.Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma.Novel p21-Activated Kinase 4 (PAK4) Allosteric Modulators Overcome Drug Resistance and Stemness in Pancreatic Ductal Adenocarcinoma.Glucose Metabolism Reprogrammed by Overexpression of IKKε Promotes Pancreatic Tumor Growth.Comparative analysis of the relative potential of silver, Zinc-oxide and titanium-dioxide nanoparticles against UVB-induced DNA damage for the prevention of skin carcinogenesis.Structure, biochemistry, and biology of PAK kinases.MiR-199a/b-3p suppresses migration and invasion of breast cancer cells by downregulating PAK4/MEK/ERK signaling pathway.Targeting polyamine biosynthetic pathway through RNAi causes the abrogation of MCF 7 breast cancer cell line.Interleukin-8 is a key mediator of FKBP51-induced melanoma growth, angiogenesis and metastasisSilver nanoparticles protect human keratinocytes against UVB radiation-induced DNA damage and apoptosis: potential for prevention of skin carcinogenesis.SHARPIN overexpression induces tumorigenesis in human prostate cancer LNCaP, DU145 and PC-3 cells via NF-κB/ERK/Akt signaling pathway.Targeting reactive oxygen species in development and progression of pancreatic cancer.MYB is a novel regulator of pancreatic tumour growth and metastasis.Paeoniflorin inhibits human pancreatic cancer cell apoptosis via suppression of MMP-9 and ERK signaling.Insights into the Role of microRNAs in Pancreatic Cancer Pathogenesis: Potential for Diagnosis, Prognosis, and Therapy.Cucurbitacin B and SCH772984 exhibit synergistic anti-pancreatic cancer activities by suppressing EGFR, PI3K/Akt/mTOR, STAT3 and ERK signaling.
P2860
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P2860
p-21 activated kinase 4 promotes proliferation and survival of pancreatic cancer cells through AKT- and ERK-dependent activation of NF-κB pathway.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
p-21 activated kinase 4 promot ...... t activation of NF-κB pathway.
@en
type
label
p-21 activated kinase 4 promot ...... t activation of NF-κB pathway.
@en
prefLabel
p-21 activated kinase 4 promot ...... t activation of NF-κB pathway.
@en
P2093
P2860
P356
P1433
P1476
p-21 activated kinase 4 promot ...... t activation of NF-κB pathway.
@en
P2093
Ajay P Singh
Arun Bhardwaj
James E Carter
Nikhil Tyagi
Seema Singh
Steven McClellan
P2860
P304
P356
10.18632/ONCOTARGET.2398
P407
P577
2014-09-01T00:00:00Z