Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles.
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The Quest for Targets Executing MYC-Dependent Cell TransformationOncosuppressive functions of decorinStrategically targeting MYC in cancerMetabolic vulnerabilities of MYC-induced cancerInteractions between Myc and MondoA transcription factors in metabolism and tumourigenesisMYC, Metabolism, and CancerPatterns of Chromosomal Aberrations in Solid TumorsMYC and metabolism on the path to cancerMYC/MIZ1-dependent gene repression inversely coordinates the circadian clock with cell cycle and proliferation.OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumorsThe Interaction of Myc with Miz1 Defines Medulloblastoma Subgroup IdentityInteraction with WDR5 promotes target gene recognition and tumorigenesis by MYCc-Myc and AMPK Control Cellular Energy Levels by Cooperatively Regulating Mitochondrial Structure and FunctionRegistered report: transcriptional amplification in tumor cells with elevated c-MycHigh-throughput single-cell gene-expression profiling with multiplexed error-robust fluorescence in situ hybridizationIdentifying core gene modules in glioblastoma based on multilayer factor-mediated dysfunctional regulatory networks through integrating multi-dimensional genomic data.Somatic polyploidy is associated with the upregulation of c-MYC interacting genes and EMT-like signatureControlling the Master: Chromatin Dynamics at the MYC Promoter Integrate Developmental SignalingMenin enhances c-Myc-mediated transcription to promote cancer progressionMice deficient of Myc super-enhancer region reveal differential control mechanism between normal and pathological growth.CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinomaThe utility of Apc-mutant rats in modeling human colon cancer.The spliceosome is a therapeutic vulnerability in MYC-driven cancer.CRY2 and FBXL3 Cooperatively Degrade c-MYC.Taming of the beast: shaping Myc-dependent amplificationTumor cell-specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligasecMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.Tipping the MYC-MIZ1 balance: targeting the HUWE1 ubiquitin ligase selectively blocks MYC-activated genes.Identification of c-MYC SUMOylation by mass spectrometry.Metabolic reprogramming in triple-negative breast cancer through Myc suppression of TXNIPsnoRNAs are a novel class of biologically relevant Myc targets.Hyperglycemia repression of miR-24 coordinately upregulates endothelial cell expression and secretion of von Willebrand factor.Redeployment of Myc and E2f1-3 drives Rb-deficient cell cyclesTelomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity.Repression of SRF target genes is critical for Myc-dependent apoptosis of epithelial cells.Physical Interactions and Functional Coordination between the Core Subunits of Set1/Mll Complexes and the Reprogramming Factors.The role of histone demethylase KDM4B in Myc signaling in neuroblastomaMINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cellsRUNX3 is oncogenic in natural killer/T-cell lymphoma and is transcriptionally regulated by MYC.Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation
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P2860
Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Activation and repression by o ...... ific gene expression profiles.
@en
type
label
Activation and repression by o ...... ific gene expression profiles.
@en
prefLabel
Activation and repression by o ...... ific gene expression profiles.
@en
P2093
P50
P356
P1433
P1476
Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles
@en
P2093
Chia-Lin Wei
Francesca Lorenzin
Frederik Roels
Hélène Dumay-Odelot
Katrin E Wiese
Lars Zender
Lukas Rycak
Marek Bartkuhn
Matthias Fischer
Saadia Karim
P2888
P304
P356
10.1038/NATURE13473
P407
P577
2014-07-09T00:00:00Z
P5875
P6179
1007164137