A nuclear transport inhibitor that modulates the unfolded protein response and provides in vivo protection against lethal dengue virus infection.
about
Apoptosis, autophagy and unfolded protein response pathways in Arbovirus replication and pathogenesisFlaviviral NS4b, chameleon and jack-in-the-box roles in viral replication and pathogenesis, and a molecular target for antiviral interventionRespiratory virus modulation of host nucleocytoplasmic transport; target for therapeutic intervention?Broad-spectrum agents for flaviviral infections: dengue, Zika and beyondThe IMPORTance of the Nucleus during Flavivirus Replication.Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import.The bioactive lipid 4-hydroxyphenyl retinamide inhibits flavivirus replicationDengue Virus Infection with Highly Neutralizing Levels of Cross-Reactive Antibodies Causes Acute Lethal Small Intestinal Pathology without a High Level of Viremia in Mice.N-Desmethylclozapine, Fluoxetine, and Salmeterol Inhibit Postentry Stages of the Dengue Virus Life Cycle.Dynamic Nucleolar Targeting of Dengue Virus Polymerase NS5 in Response to Extracellular pHEffect of modulation of unfolded protein response pathway on dengue virus infection.The role of the unfolded protein response in dengue virus pathogenesis.Evaluation of Sofosbuvir (β-D-2'-deoxy-2'-α-fluoro-2'-β-C-methyluridine) as an inhibitor of Dengue virus replication.Amino acid substitutions in the non-structural proteins 4A or 4B modulate the induction of autophagy in West Nile virus infected cells independently of the activation of the unfolded protein response.Antiviral activity of N-(4-hydroxyphenyl) retinamide (4-HPR) against Zika virus.Novel inhibitors targeting Venezuelan equine encephalitis virus capsid protein identified using In Silico Structure-Based-Drug-Design.Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus V.
P2860
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P2860
A nuclear transport inhibitor that modulates the unfolded protein response and provides in vivo protection against lethal dengue virus infection.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
A nuclear transport inhibitor ...... lethal dengue virus infection.
@en
type
label
A nuclear transport inhibitor ...... lethal dengue virus infection.
@en
prefLabel
A nuclear transport inhibitor ...... lethal dengue virus infection.
@en
P2093
P2860
P50
P356
P1476
A nuclear transport inhibitor ...... lethal dengue virus infection
@en
P2093
Belinda Maher
Caroline Hick
Chunxiao Wang
Satoru Watanabe
Subhash G Vasudevan
Wing Ki Kitti Chan
P2860
P304
P356
10.1093/INFDIS/JIU319
P407
P50
P577
2014-06-05T00:00:00Z