The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation. - Test2 - elhamkhani - TriplyDB

The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.

The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.

http://www.wikidata.org/entity/Q38990833

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Aberrant GLI1 Activation in DNA Damage Response, Carcinogenesis and Chemoresistance The role of GLI1 for 5-Fu resistance in colorectal cancer Aspirin inhibits the SHH/GLI1 signaling pathway and sensitizes malignant glioma cells to temozolomide therapy.GLI1-mediated regulation of side population is responsible for drug resistance in gastric cancer When will resistance be futile?Variant allele frequency enrichment analysis in vitro reveals sonic hedgehog pathway to impede sustained temozolomide response in GBM Quantitative profiling of human renal UDP-glucuronosyltransferases and glucuronidation activity: a comparison of normal and tumoral kidney tissues Hedgehog/GLI and PI3K signaling in the initiation and maintenance of chronic lymphocytic leukemia.Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update A genome scale RNAi screen identifies GLI1 as a novel gene regulating vorinostat sensitivity.Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer.BMP signalling differentially regulates distinct haematopoietic stem cell types The Hedgehog pathway: role in cell differentiation, polarity and proliferation A novel function of the human oncogene Stil: Regulation of PC12 cell toxic susceptibility through the Shh pathway Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas.BMP and Hedgehog Regulate Distinct AGM Hematopoietic Stem Cells Ex Vivo.Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E.A sesquiterpene lactone from Siegesbeckia glabrescens suppresses Hedgehog/Gli-mediated transcription in pancreatic cancer cells.MiR-424 and miR-27a increase TRAIL sensitivity of acute myeloid leukemia by targeting PLAG1 Targeting the PI3K/AKT pathway via GLI1 inhibition enhanced the drug sensitivity of acute myeloid leukemia cells.Acute myeloid leukemia - strategies and challenges for targeting oncogenic Hedgehog/GLI signaling Sonidegib: mechanism of action, pharmacology, and clinical utility for advanced basal cell carcinomas.The eukaryotic translation initiation factor eIF4E in the nucleus: taking the road less traveled.Hedgehog signaling in cancer stem cells: a focus on hematological cancers.Targeting of the Hedgehog pathway in myeloid malignancies: still a worthy chase?Nuclear expression of Gli-1 is predictive of pathologic complete response to chemoradiation in trimodality treated oesophageal cancer patients.Reduced proliferation and colony formation of head and neck squamous cell carcinoma (HNSCC) after dual targeting of EGFR and hedgehog pathways.Inhibition of MicroRNA-149-5p Induces Apoptosis of Acute Myeloid Leukemia Cell Line THP-1 by Targeting Fas Ligand (FASLG).Suppression of GLI sensitizes medulloblastoma cells to mitochondria-mediated apoptosis Small-molecule Hedgehog inhibitor attenuates the leukemia-initiation potential of acute myeloid leukemia cells.Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia.Multidrug-resistant cancer cells and cancer stem cells hijack cellular systems to circumvent systemic therapies, can natural products reverse this?MicroRNA-326 Sensitizes Human Glioblastoma Cells to Curcumin via the SHH/GLI1 Signaling Pathway.The eukaryotic translation initiation factor eIF4E wears a "cap" for many occasions.GLI2 inhibition abrogates human leukemia stem cell dormancy.Molecular Pathways: GLI1-Induced Drug Glucuronidation in Resistant Cancer Cells.Rational for targeting the hedgehog signalling pathway in acute myeloid leukemia with FLT3 mutation Synthesis of ribavirin 2'-Me-C-nucleoside analogues Transcriptome analysis of G protein-coupled receptors in distinct genetic subgroups of acute myeloid leukemia: identification of potential disease-specific targets.Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML

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P2860

The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.

http://www.wikidata.org/entity/Q38990833

description

2014 nî lūn-bûn

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年學術文章

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2014年學術文章

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2014年學術文章

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The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.

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The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.

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The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.

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The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.

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Abdellatif Amri

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Andrea A Romeo

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Biljana Culjkovic-Kraljacic

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Craig T Jordan

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Eftihia Cocolakis

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Gregory Cormack

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Hiba Ahmad Zahreddine

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James B Jaquith

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Julie Bergeron

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Katherine L B Borden

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P2860

Differential expression analysis for sequence count data

Human UDP-glucuronosyltransferases: metabolism, expression, and disease

3'-azido-3'-deoxythimidine (AZT) is glucuronidated by human UDP-glucuronosyltransferase 2B7 (UGT2B7)

Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.

Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap

Management of acute myeloid leukemia in elderly patients.

Acute myeloid leukemia: epidemiology and etiology.

Ribavirin uptake by human erythrocytes and the involvement of nitrobenzylthioinosine-sensitive (es)-nucleoside transporters.

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists.

Treatment decision-making for older patients with high-risk myelodysplastic syndrome or acute myeloid leukemia: problems and approaches.

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7507

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