Id4 dependent acetylation restores mutant-p53 transcriptional activity.
about
Inhibitor of differentiation 4 (ID4) inactivation promotes de novo steroidogenesis and castration-resistant prostate cancer.Increased ID4 expression, accompanied by mutant p53 accumulation and loss of BRCA1/2 proteins in triple-negative breast cancer, adversely affects survival.Opposite effects of HDAC5 and p300 on MRTF-A-related neuronal apoptosis during ischemia/reperfusion injury in rats.Inhibitor of differentiation 4 (ID4): From development to cancerInactivation of ID4 promotes a CRPC phenotype with constitutive AR activation through FKBP52.ID4 regulates transcriptional activity of wild type and mutant p53 via K373 acetylationBasic helix loop helix (bHLH) transcription factor 3 (TCF3, E2A) is regulated by androgens in prostate cancer cells.Inhibitor of differentiation 4 (ID4) acts as an inhibitor of ID-1, -2 and -3 and promotes basic helix loop helix (bHLH) E47 DNA binding and transcriptional activity.EZH2 dependent H3K27me3 is involved in epigenetic silencing of ID4 in prostate cancer.Molecular mechanisms of nutlin-3 involve acetylation of p53, histones and heat shock proteins in acute myeloid leukemia.Intra-tumoral delivery of functional ID4 protein via PCL/maltodextrin nano-particle inhibits prostate cancer growthID4 promotes AR expression and blocks tumorigenicity of PC3 prostate cancer cells.Inhibitor of Differentiation-3 and Estrogenic Endocrine Disruptors: Implications for Susceptibility to Obesity and Metabolic Disorders.
P2860
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P2860
Id4 dependent acetylation restores mutant-p53 transcriptional activity.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Id4 dependent acetylation restores mutant-p53 transcriptional activity.
@en
Id4 dependent acetylation restores mutant-p53 transcriptional activity.
@nl
type
label
Id4 dependent acetylation restores mutant-p53 transcriptional activity.
@en
Id4 dependent acetylation restores mutant-p53 transcriptional activity.
@nl
prefLabel
Id4 dependent acetylation restores mutant-p53 transcriptional activity.
@en
Id4 dependent acetylation restores mutant-p53 transcriptional activity.
@nl
P2093
P2860
P356
P1433
P1476
Id4 dependent acetylation restores mutant-p53 transcriptional activity.
@en
P2093
Ashley E Knowell
Derrick J Morton
Divya Patel
Jaideep Chaudhary
Pankaj Sharma
Shanora Glymph
P2860
P2888
P356
10.1186/1476-4598-12-161
P577
2013-12-13T00:00:00Z
P5875
P6179
1014823255