New Insights into the Physiological Role of Endoplasmic Reticulum-Associated Degradation.
about
ER-associated degradation is required for vasopressin prohormone processing and systemic water homeostasis.Mice deficient for ERAD machinery component Sel1L develop central diabetes insipidus.Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes.Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity.Transcriptome and functional analysis in a Drosophila model of NGLY1 deficiency provides insight into therapeutic approaches.Pharmacoperones as Novel Therapeutics for Diverse Protein Conformational Diseases.A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates.SIL1, the endoplasmic-reticulum-localized BiP co-chaperone, plays a crucial role in maintaining skeletal muscle proteostasis and physiology.Coordinate regulation of mutant NPC1 degradation by selective ER autophagy and MARCH6-dependent ERAD
P2860
Q47111673-5FBACA1A-651E-4D15-951D-6B424EBD7534Q47787403-C3810584-B749-4832-AC3B-B9F7E11D6E73Q48152192-9198C584-01BB-4CF9-82F5-4BFD6B536E08Q49851092-E13C87FD-4FAF-48A9-9832-A68C65762FDAQ49964423-494DEE4B-5E72-439A-8ADC-08BF8E9CDA6FQ50014672-6EFAE91F-7B28-4B6A-B253-C7D03D644AA4Q52668654-5E519DAB-F9C3-422F-A8AC-59C3B409E2FDQ52691416-4C21E3F6-A8BA-48C1-8E9C-89596813A78CQ57082926-2520BA58-4310-4790-977A-615C65DC702A
P2860
New Insights into the Physiological Role of Endoplasmic Reticulum-Associated Degradation.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
New Insights into the Physiological Role of Endoplasmic Reticulum-Associated Degradation.
@en
New Insights into the Physiological Role of Endoplasmic Reticulum-Associated Degradation.
@nl
type
label
New Insights into the Physiological Role of Endoplasmic Reticulum-Associated Degradation.
@en
New Insights into the Physiological Role of Endoplasmic Reticulum-Associated Degradation.
@nl
prefLabel
New Insights into the Physiological Role of Endoplasmic Reticulum-Associated Degradation.
@en
New Insights into the Physiological Role of Endoplasmic Reticulum-Associated Degradation.
@nl
P2860
P1476
New Insights into the Physiological Role of Endoplasmic Reticulum-Associated Degradation.
@en
P2093
Billy Tsai
Peter Arvan
P2860
P304
P356
10.1016/J.TCB.2016.12.002
P50
P577
2017-02-09T00:00:00Z