Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1.
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New insights into an X-traordinary viral proteinMechanism of allosteric activation of SAMHD1 by dGTPStructural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolaseRegulation of deoxynucleotide metabolism in cancer: novel mechanisms and therapeutic implicationsThe Expression of Functional Vpx during Pathogenic SIVmac Infections of Rhesus Macaques Suppresses SAMHD1 in CD4+ Memory T CellsFunctional organization of human SAMHD1 and mechanisms of HIV-1 restrictionThe ribonuclease activity of SAMHD1 is required for HIV-1 restrictionMacaques as model hosts for studies of HIV-1 infectionModerate restriction of macrophage-tropic human immunodeficiency virus type 1 by SAMHD1 in monocyte-derived macrophages.Cyclin F/FBXO1 Interacts with HIV-1 Viral Infectivity Factor (Vif) and Restricts Progeny Virion Infectivity by Ubiquitination and Proteasomal Degradation of Vif Protein through SCFcyclin F E3 Ligase MachineryIdentification of cellular proteins interacting with the retroviral restriction factor SAMHD1GTP activator and dNTP substrates of HIV-1 restriction factor SAMHD1 generate a long-lived activated stateA cell-intrinsic inhibitor of HIV-1 reverse transcription in CD4(+) T cells from elite controllersSAMHD1 protects cancer cells from various nucleoside-based antimetabolites.Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility.SAMHD1 specifically affects the antiviral potency of thymidine analog HIV reverse transcriptase inhibitorsMouse knockout models for HIV-1 restriction factors.Modulation of LINE-1 and Alu/SVA retrotransposition by Aicardi-Goutières syndrome-related SAMHD1.SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage.SAMHD1 prevents autoimmunity by maintaining genome stability.The eukaryotic elongation factor eEF1A1 interacts with SAMHD1.MicroRNA-181 contributes to downregulation of SAMHD1 expression in CD4+ T-cells derived from Sèzary syndrome patients.Structural basis of allosteric activation of sterile α motif and histidine-aspartate domain-containing protein 1 (SAMHD1) by nucleoside triphosphates.Tissue myeloid cells in SIV-infected primates acquire viral DNA through phagocytosis of infected T cells.Cyclin L2 is a critical HIV dependency factor in macrophages that controls SAMHD1 abundance.Distinct characteristics of endometrial and decidual macrophages and regulation of their permissivity to HIV-1 infection by SAMHD1.Endogenous CCL2 neutralization restricts HIV-1 replication in primary human macrophages by inhibiting viral DNA accumulationSAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells.Low SAMHD1 expression following T-cell activation and proliferation renders CD4+ T cells susceptible to HIV-1.Molecular determinants for recognition of divergent SAMHD1 proteins by the lentiviral accessory protein Vpx.SAMHD1 specifically restricts retroviruses through its RNase activity.Complement-Opsonized HIV-1 Overcomes Restriction in Dendritic Cells.SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation.Subversion of Cell Cycle Regulatory Mechanisms by HIV.Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction.The Frequency of Cytidine Editing of Viral DNA Is Differentially Influenced by Vpx and Nucleosides during HIV-1 or SIVMAC Infection of Dendritic Cells.CyclinA2-Cyclin-dependent Kinase Regulates SAMHD1 Protein Phosphohydrolase Domain.Gut microbiota lipopolysaccharide accelerates inflamm-aging in mice.Understanding Factors That Modulate the Establishment of HIV Latency in Resting CD4+ T-Cells In Vitro.The G1/S Specific Cyclin D2 Is a Regulator of HIV-1 Restriction in Non-proliferating Cells.
P2860
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P2860
Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Phosphorylation of SAMHD1 by c ...... riction activity toward HIV-1.
@en
Phosphorylation of SAMHD1 by c ...... riction activity toward HIV-1.
@nl
type
label
Phosphorylation of SAMHD1 by c ...... riction activity toward HIV-1.
@en
Phosphorylation of SAMHD1 by c ...... riction activity toward HIV-1.
@nl
prefLabel
Phosphorylation of SAMHD1 by c ...... riction activity toward HIV-1.
@en
Phosphorylation of SAMHD1 by c ...... riction activity toward HIV-1.
@nl
P2093
P1433
P1476
Phosphorylation of SAMHD1 by c ...... triction activity toward HIV-1
@en
P2093
Alexandra Cribier
Ana Luiza Chaves Valadão
Benjamin Descours
Monsef Benkirane
P304
P356
10.1016/J.CELREP.2013.03.017
P577
2013-04-17T00:00:00Z