about
3-Hydroxypyridinone derivatives as metal-sequestering agents for therapeutic use.Recent progress in repositioning Alzheimer's disease drugs based on a multitarget strategy.New Tacrine Hybrids with Natural-Based Cysteine Derivatives as Multitargeted Drugs for Potential Treatment of Alzheimer's Disease.New bifunctional metalloproteinase inhibitors: an integrated approach towards biological improvements and cancer therapy.Multifunctional iron-chelators with protective roles against neurodegenerative diseases.Hydroxypyridinone derivatives: a fascinating class of chelators with therapeutic applications - an update.Complexes of hydroxy(thio)pyrone and hydroxy(thio)pyridinone with Zn(II) and Mo(VI). Thermodynamic stability and insulin-mimetic activity.New tris(hydroxypyridinones) as iron and aluminium sequestering agents: synthesis, complexation and in vivo studies.A bis(3-hydroxy-4-pyridinone)-EDTA derivative as a strong chelator for M3+ hard metal ions: complexation ability and selectivity.Combined chelation based on glycosyl-mono- and bis-hydroxypyridinones for aluminium mobilization: solution and biodistribution studies.N-Carboxyalkyl derivatives of 3-hydroxy-4-pyridinones: synthesis, complexation with Fe(III), Al(III) and Ga(III) and in vivo evaluation.Alkylaryl-amino derivatives of 3-hydroxy-4-pyridinones as aluminium chelating agents with potential clinical application.Iminodiacetyl-hydroxamate derivatives as metalloproteinase inhibitors: equilibrium complexation studies with Cu(II), Zn(II) and Ni(II).N-Arylamine derivatives of 3-hydroxy-4-pyridinones: solution studies and bioevaluation in view of Al-detoxification roles.New silica-immobilized hydroxypyrimidinone as sorbent of hard metal ions from aqueous fluids.Bifunctional 3-hydroxy-4-pyridinone derivatives as potential pharmaceuticals: synthesis, complexation with Fe(III), Al(III) and Ga(III) and in vivo evaluation with 67Ga.Biologically relevant O,S-donor compounds. Synthesis, molybdenum complexation and xanthine oxidase inhibition.Copper(II) complexation of tacrine hybrids with potential anti-neurodegenerative roles.Tacrine-(hydroxybenzoyl-pyridone) hybrids as potential multifunctional anti-Alzheimer's agents: AChE inhibition, antioxidant activity and metal chelating capacity.Hydroxypyridinone-benzofuran hybrids with potential protective roles for Alzheimer´s disease therapy.Hydroxy(thio)pyrone and hydroxy(thio)pyridinone iron chelators: physico-chemical properties and anti-oxidant activity.Tacrine-deferiprone hybrids as multi-target-directed metal chelators against Alzheimer's disease: a two-in-one drugNew tris-3,4-HOPO lanthanide complexes as potential imaging probes: complex stability and magnetic propertiesA new tripodal-3-hydroxy-4-pyridinone for iron and aluminium sequestration: synthesis, complexation and in vivo studiesA novel tripodal tris-hydroxypyrimidinone sequestering agent for trivalent hard metal ions: synthesis, complexation and in vivo studiesBifunctional 3-hydroxy-4-pyridinone derivatives as potential pharmaceuticals: synthesis, complexation with Fe(III), Al(III) and Ga(III) and in vivo evaluation with 67GaElectron spin resonance studies and crystal structures of copper(II) complexes of some 12-, 13- and 14-membered oxatriaza macrocyclesA gallium complex with a new tripodal tris-hydroxypyridinone for potential nuclear diagnostic imaging: solution and in vivo studies of 67Ga-labeled species1-Oxa-4,8,12-triazacyclotetradecane-4,12-diacetic acid (H2L2): studies on protonation and metal complexation; crystal structure of [CuL2]·5H2OThe stability of the metal complexes of cyclic tetra-aza tetra-acetic acidsNew Multitarget Hybrids Bearing Tacrine and Phenylbenzothiazole Motifs as Potential Drug Candidates for Alzheimer's DiseaseDesign, Synthesis, and In Vitro Evaluation of Hydroxybenzimidazole-Donepezil Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's DiseaseNew strong extrafunctionalizable tris(3,4-HP) and bis(3,4-HP) metal sequestering agents: synthesis, solution and in vivo metal chelationDonepezil structure-based hybrids as potential multifunctional anti-Alzheimer's drug candidatesNovel tacrine-benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer's Disease
P50
Q38397352-58093D55-58D6-4F16-AF05-E73F82643027Q38806779-619A682B-DFF3-41F8-8DF0-61B9F360E7D8Q38845131-5C53956C-B16B-40E4-B80C-6A9DF208A76BQ39164036-C6F67ACB-58D4-4356-BFB4-1F8C05E8BC4BQ39181472-AACAD477-A1CD-47A9-A2D1-C6342DBFF940Q39209055-4E1991BA-8F91-4DC4-A96D-197138D48B4FQ42822270-14B598B8-F573-4B3C-91D7-4559A52E8281Q42954213-7705B8AD-E0B8-4C51-804A-B32491F0CB5DQ43071045-8F26B18C-8B91-4B68-B7C5-73C431D46BE6Q43277699-F76AC285-CC2A-4349-92BC-EAD9A9F6218EQ44136296-5A6C0484-8BA8-4E8D-8705-F1E9DF0A8182Q44595046-1ED2B3CA-6623-49FF-A7A3-BAA28A861569Q44624696-8B446A3D-545B-48E9-8C14-D584769A72CBQ45083824-C248AC3E-A900-45A5-93A5-BC122EEEC76AQ46624211-9834C184-E900-45E9-A76C-A2D6DE3F789BQ46679096-856A778F-F7A4-40FC-89B5-20BF824A3C81Q46691450-4E2A6151-1D44-47F6-B719-F4F6FE536989Q46708464-1DC7F31D-D29C-4554-B9CB-56ED4BCC988EQ46843133-0DBE2327-39C3-4A45-BF2D-A5A6AE8FF872Q49573041-80A52C12-34E6-48A7-9DC7-CD3FBC0501E6Q54515981-D0A2480A-692D-4525-BA40-317AD80635DAQ57453972-E73DDCC8-1058-41B0-9D6A-32EFE7DE1EC3Q58374529-328BB9D3-6907-42AA-AC18-60A7E1ED1092Q59166605-23DC77E7-9E7C-469C-8119-8C440E8235FBQ59166652-0919F0C3-724F-425E-96C3-69EA78E1A8F7Q59166764-B81BE3BE-BCF9-48CE-B824-30FC40E95F9DQ61755436-7A4369FB-4B1C-461E-811F-81E172800206Q63197554-6B50443F-345B-4109-BAD9-AE78754B6987Q63197561-C332EC4D-55F7-40E2-8C2A-B7EAB89A1CDAQ63197563-2E5A7A6F-7A41-4EF5-9F5E-038D6C8EA687Q64269971-84948D50-6046-473C-BCB7-F9609FFC4469Q89880116-5629C5AD-65BA-48B6-A9F7-F5787161C4C2Q90435205-70D321AA-571F-42E7-89AD-FE3FB907BCFDQ91218741-F7D71832-B837-4C80-9218-9DAB997CC720Q91418587-0CD15687-417D-43AD-B0CE-8D35BBA4DC8C
P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Sílvia Chaves
@ast
Sílvia Chaves
@en
Sílvia Chaves
@es
Sílvia Chaves
@nl
Sílvia Chaves
@sl
type
label
Sílvia Chaves
@ast
Sílvia Chaves
@en
Sílvia Chaves
@es
Sílvia Chaves
@nl
Sílvia Chaves
@sl
prefLabel
Sílvia Chaves
@ast
Sílvia Chaves
@en
Sílvia Chaves
@es
Sílvia Chaves
@nl
Sílvia Chaves
@sl
P1053
F-9097-2014
P106
P1153
7003574012
P21
P31
P3829
P496
0000-0002-8554-4992