Silencing of the WFS1 gene in HEK cells induces pathways related to neurodegeneration and mitochondrial damage.

about

Role of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram Syndrome Recent Insights into the Role of Unfolded Protein Response in ER Stress in Health and Disease.

P2860

Q27342152-B387C619-BF21-4E8D-8306-0C0A76662781 Q33653691-51848F6A-FB66-4ACD-87EF-F6D8DADCC22A

P2860

Silencing of the WFS1 gene in HEK cells induces pathways related to neurodegeneration and mitochondrial damage.

Item

http://www.wikidata.org/entity/Q39210046

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

Silencing of the WFS1 gene in ...... tion and mitochondrial damage.

@en

Silencing of the WFS1 gene in ...... tion and mitochondrial damage.

@nl

type

Item

label

Silencing of the WFS1 gene in ...... tion and mitochondrial damage.

@en

Silencing of the WFS1 gene in ...... tion and mitochondrial damage.

@nl

prefLabel

Silencing of the WFS1 gene in ...... tion and mitochondrial damage.

@en

Silencing of the WFS1 gene in ...... tion and mitochondrial damage.

@nl

P1476

Silencing of the WFS1 gene in ...... tion and mitochondrial damage.

@en

P2093

Leo C Schalkwyk

http://www.w3.org/2001/XMLSchema#string

Mithu Guha

http://www.w3.org/2001/XMLSchema#string

P2860

Diabetes insipidus, diabetes mellitus, optic atrophy and deafness (DIDMOAD) caused by mutations in a novel gene (wolframin) coding for a predicted transmembrane protein

Wolframin expression induces novel ion channel activity in endoplasmic reticulum membranes and increases intracellular calcium

Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells

WFS1 protein modulates the free Ca(2+) concentration in the endoplasmic reticulum

A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis

Krüppel-like transcription factor 4 contributes to maintenance of telomerase activity in stem cells

Statistical significance for genomewide studies

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells

Wfs1 gene deletion causes growth retardation in mice and interferes with the growth hormone pathway

P304

182-190

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1152/PHYSIOLGENOMICS.00122.2012

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

P577

2013-01-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

234141515

http://www.w3.org/2001/XMLSchema#string

P698

23321269

http://www.w3.org/2001/XMLSchema#string

P921

gene silencing

Silencing of the WFS1 gene in HEK cells induces pathways related to neurodegeneration and mitochondrial damage.

about

P2860

P2860

Silencing of the WFS1 gene in HEK cells induces pathways related to neurodegeneration and mitochondrial damage.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P921

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P921