A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
about
The Emerging Role of Branched-Chain Amino Acids in Insulin Resistance and MetabolismPotential roles of GPR120 and its agonists in the management of diabetesOmega-3 Fatty Acids and FFAR4A Variant of GJD2, Encoding for Connexin 36, Alters the Function of Insulin Producing β-CellsBranched-chain amino acids in metabolic signalling and insulin resistancePharmacogenomics in diabetes mellitus: insights into drug action and drug discoveryThe diabetes susceptibility gene Clec16a regulates mitophagyGLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein BimGenomic Footprints in Selected and Unselected Beef Cattle Breeds in Korea.Precise Network Modeling of Systems Genetics Data Using the Bayesian Network Webserver.A central role for GRB10 in regulation of islet function in man.GPR120 (FFAR4) is preferentially expressed in pancreatic delta cells and regulates somatostatin secretion from murine islets of Langerhans.GeneTopics--interpretation of gene sets via literature-driven topic modelsMoving on from GWAS: functional studies on the G6PC2 gene implicated in the regulation of fasting blood glucose.Genome-wide association study for feed efficiency and growth traits in U.S. beef cattleSox5 regulates beta-cell phenotype and is reduced in type 2 diabetesEffects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets.Detection of type 2 diabetes related modules and genes based on epigenetic networksMultiple functional polymorphisms in the G6PC2 gene contribute to the association with higher fasting plasma glucose levels.Alteration of the glucagon axis in GPR120 (FFAR4) knockout mice: a role for GPR120 in glucagon secretion.Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolismDownregulation of type II diabetes mellitus and maturity onset diabetes of young pathways in human pancreatic islets from hyperglycemic donors.Targets and candidate agents for type 2 diabetes treatment with computational bioinformatics approach.Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.The pancreatic β cell: recent insights from human genetics.Association of secreted frizzled-related protein 4 (SFRP4) with type 2 diabetes in patients with stable coronary artery diseaseDNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic isletsβ-Cell inflammation in human type 2 diabetes and the role of autophagy.Differential Gene Expression in GPR40-Overexpressing Pancreatic β-cells Treated with Linoleic Acid.Identifying module biomarker in type 2 diabetes mellitus by discriminative area of functional activity.Genetics of type 2 diabetes-pitfalls and possibilities.A MATLAB tool for pathway enrichment using a topology-based pathway regulation score.Functional analysis of free fatty acid receptor GPR120 in human eosinophils: implications in metabolic homeostasis.Human gastroenteropancreatic expression of melatonin and its receptors MT1 and MT2.Analysis artefacts of the INS-IGF2 fusion transcript.Integrative enrichment analysis: a new computational method to detect dysregulated pathways in heterogeneous samples.Nuclear factor κB-inducing kinase activation as a mechanism of pancreatic β cell failure in obesity.Rfx6 maintains the functional identity of adult pancreatic β cells.Transcriptional Regulation of the Pancreatic Islet: Implications for Islet Function.Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis.
P2860
Q26744725-FB61B36D-4DBC-4078-BB25-81D9FD683024Q26827101-FDB55A30-16C5-4906-A2F0-88989330DAEDQ27000272-24D5F0A6-A2B7-403A-9EBD-A95E957DA3BAQ27318557-F4E31D3A-ABAF-4FBF-994C-064912E06C05Q28249276-EDBE2545-1BC4-4882-8720-FE5EEEA26AC2Q28274686-1C58B7E2-B94C-4337-B4B9-317909A2C220Q28511990-4F1EC5F7-C63A-44B4-A18C-B60340C4BB35Q28571413-E199B37B-9603-4D4C-8919-BC5204D18D38Q30386173-EAEAF5F6-8728-4ECA-9C12-978445C6E96AQ31147701-26E503E8-8AFA-4351-B7C6-3ED55880FFA1Q31156020-D2D59676-4D45-43E3-B925-CC748323F1E5Q33600207-3FBDE07B-35BB-4AA8-B45C-E267920D14F4Q33642727-1028F7B9-41E3-4A7F-98FB-A09267C0506BQ33699177-E2DF8A31-B028-4492-9096-442843F8B025Q33706506-00BD1AC8-F379-4CA1-B5E6-4CA5316806CAQ33786322-73F8B5E4-5256-45E9-A699-02E5F254E68BQ33787509-5621C0CF-4F9D-47B7-A5EA-4362C9ED9B74Q33840761-CF8F2B79-5A22-4096-9B63-7126BA7D2B55Q33930004-76444EA9-B3F2-4552-8CB7-6945184A11E0Q34076033-EFF9A164-74CD-4215-A347-E9999966F305Q34281205-035FA37C-6C2A-4D9E-A1D5-CD50AB69ED4CQ34419372-DF37F084-8DF0-45FB-A2A7-CB917110B5C8Q34460943-0CAF6026-719A-4D04-86A8-24F2127BADC5Q34464568-6908EFD4-2A0F-4A29-A351-08F375ACB4B2Q34499691-AE8DE09E-DB6E-4709-8246-0CDFB675BC94Q34586921-69408BBD-6297-4186-8F96-2A7282E87DB2Q34859889-2CB10F67-3222-4E79-AAB9-629190F9A1A6Q34977998-BC396B9F-7ACC-4859-ADA5-817D20A57191Q35127471-78994896-0B69-4540-8A69-3E4B4EAE37D1Q35218961-1D9E7B26-74BF-4ED4-A7C6-56486093D3DAQ35227765-6443625E-2488-426B-AC0F-E00065A4549AQ35389956-D6F26716-9AE4-4EB1-B427-A871E1352374Q35581513-74887BE3-38F2-4604-BD55-1E9C07A8E118Q35590120-3DDCB463-F6A5-4284-A75F-49A6A9C3CE5FQ35721708-61DB2220-FB11-4755-9038-697362748BA4Q35837792-63AA0E50-87FD-4A00-8536-232CEEA5E233Q35894344-07D89FCF-D6AC-4CFC-B3F6-C65BBC5BAAD8Q35973399-037E7889-CB61-4694-ACE6-9C27624C0C79Q36121381-8288C580-6E61-4976-915C-544502A9C454Q36206751-798F7E19-76CD-42A0-A5F4-25718A8742B0
P2860
A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
A systems genetics approach id ...... pe 2 diabetes in human islets.
@en
A systems genetics approach id ...... pe 2 diabetes in human islets.
@nl
type
label
A systems genetics approach id ...... pe 2 diabetes in human islets.
@en
A systems genetics approach id ...... pe 2 diabetes in human islets.
@nl
prefLabel
A systems genetics approach id ...... pe 2 diabetes in human islets.
@en
A systems genetics approach id ...... pe 2 diabetes in human islets.
@nl
P2093
P50
P1433
P1476
A systems genetics approach id ...... pe 2 diabetes in human islets.
@en
P2093
Amitabh Sharma
Anders Rosengren
Arvind Soni
Claes B Wollheim
Emma Ahlqvist
Erik Renström
Hemang Parikh
Jonathan L S Esguerra
Petter Vikman
Stefan Lang
P304
P356
10.1016/J.CMET.2012.06.006
P50
P577
2012-07-01T00:00:00Z