Role of the integrin-linked kinase (ILK)/Rictor complex in TGFβ-1-induced epithelial-mesenchymal transition (EMT).
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Mechanisms of TGFβ-Induced Epithelial-Mesenchymal TransitionExtracellular matrix as a contextual determinant of transforming growth factor-β signaling in epithelial-mesenchymal transition and in cancerEndothelial Rictor is crucial for midgestational development and sustained and extensive FGF2-induced neovascularization in the adult.mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling AxisAdhesion rings surround invadopodia and promote maturation.DACH1 inhibits SNAI1-mediated epithelial-mesenchymal transition and represses breast carcinoma metastasis.Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma.Rictor is an independent prognostic factor for endometrial carcinoma.Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins.Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines.A critical role for the mTORC2 pathway in lung fibrosis.Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion.The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-β-Induced Epithelial to Mesenchymal Transition.Tubular cell phenotype in HIV-associated nephropathy: role of phospholipid lysophosphatidic acid.Defining the Domain Arrangement of the Mammalian Target of Rapamycin Complex Component Rictor Protein.Reprogramming during epithelial to mesenchymal transition under the control of TGFβCrossroads of integrins and cadherins in epithelia and stroma remodeling.Effects of lentiviral RNA interference-mediated downregulation of integrin-linked kinase on biological behaviors of human lens epithelial cells.Mechanisms that link the oncogenic epithelial-mesenchymal transition to suppression of anoikis.Silencing of ILK attenuates the abnormal proliferation and migration of human Tenon's capsule fibroblasts induced by TGF-β2.Integrin-linked kinase as a novel molecular switch of the IL-6-NF-κB signaling loop in breast cancer.Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase.The metastasis suppressor CD82/KAI1 inhibits fibronectin adhesion-induced epithelial-to-mesenchymal transition in prostate cancer cells by repressing the associated integrin signaling.Crosstalk between breast cancer stem cells and metastatic niche: emerging molecular metastasis pathway?Pro-fibrotic pathway activation in trabecular meshwork and lamina cribrosa is the main driving force of glaucoma.Regulation of oncogenic KRAS signaling via a novel KRAS-integrin-linked kinase-hnRNPA1 regulatory loop in human pancreatic cancer cells.Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix.Role of integrin-linked kinase in drug resistance of lung cancer.Common pathway signature in lung and liver fibrosis.The mammalian target of rapamycin signaling pathway regulates myocyte enhancer factor-2C phosphorylation levels through integrin-linked kinase in goat skeletal muscle satellite cells.Integrin-linked kinase links dynactin-1/dynactin-2 with cortical integrin receptors to orient the mitotic spindle relative to the substratum.Integrins and Cell Metabolism: An Intimate Relationship Impacting Cancer.ILK-PI3K/AKT pathway participates in cutaneous wound contraction by regulating fibroblast migration and differentiation to myofibroblast.Exploring the role of sphingolipid machinery during the epithelial to mesenchymal transition program using an integrative approachTargeting mTORC2 component rictor inhibits cell proliferation and promotes apoptosis in gastric cancer.Hic-5 regulates epithelial to mesenchymal transition in ovarian cancer cells in a TGFβ1-independent manner.miR-185 Inhibits Fibrogenic Activation of Hepatic Stellate Cells and Prevents Liver Fibrosis.Overexpression of Rictor protein in colorectal cancer is correlated with tumor progression and prognosis.Clinical and genomic landscape of gastric cancer with a mesenchymal phenotype.
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Role of the integrin-linked kinase (ILK)/Rictor complex in TGFβ-1-induced epithelial-mesenchymal transition (EMT).
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Role of the integrin-linked ki ...... -mesenchymal transition (EMT).
@en
Role of the integrin-linked kinase
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type
label
Role of the integrin-linked ki ...... -mesenchymal transition (EMT).
@en
Role of the integrin-linked kinase
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prefLabel
Role of the integrin-linked ki ...... -mesenchymal transition (EMT).
@en
Role of the integrin-linked kinase
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P2093
P2860
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Role of the integrin-linked ki ...... l-mesenchymal transition (EMT)
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P2860
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10.1038/ONC.2012.30
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P50
P577
2012-02-06T00:00:00Z