The RAX/PACT-PKR stress response pathway promotes p53 sumoylation and activation, leading to G₁ arrest
about
Sumoylation in gene regulation, human disease, and therapeutic action.PKR regulates proliferation, differentiation, and survival of murine hematopoietic stem/progenitor cellsPKR is activated by cellular dsRNAs during mitosis and acts as a mitotic regulatorIncreased expression of the dsRNA-activated protein kinase PKR in breast cancer promotes sensitivity to doxorubicindsRNA binding protein PACT/RAX in gene silencing, development and diseases.A Critical Role of the mTOR/eIF2α Pathway in Hypoxia-Induced Pulmonary Hypertension.Protein-Binding Function of RNA-Dependent Protein Kinase Promotes Proliferation through TRAF2/RIP1/NF-κB/c-Myc Pathway in Pancreatic β cellsPKR inhibits the DNA damage response, and is associated with poor survival in AML and accelerated leukemia in NHD13 mice.The mechanism of Jurkat cells apoptosis induced by Aggregatibacter actinomycetemcomitans cytolethal distending toxin.DBC1 does not function as a negative regulator of SIRT1 in liver cancer.dsRNA-dependent protein kinase PKR and its role in stress, signaling and HCV infection.The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development.HIPK1 drives p53 activation to limit colorectal cancer cell growth.Double-stranded RNA-dependent protein kinase signalling and paradigms of cardiometabolic syndrome.SUMOylation of p53 mediates interferon activitiesClinical and therapeutic potential of protein kinase PKR in cancer and metabolism.PKR negatively regulates leukemia progression in association with PP2A activation, Bcl-2 inhibition and increased apoptosis.
P2860
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P2860
The RAX/PACT-PKR stress response pathway promotes p53 sumoylation and activation, leading to G₁ arrest
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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name
The RAX/PACT-PKR stress respon ...... tivation, leading to G₁ arrest
@en
The RAX/PACT-PKR stress respon ...... ivation, leading to G₁ arrest.
@nl
type
label
The RAX/PACT-PKR stress respon ...... tivation, leading to G₁ arrest
@en
The RAX/PACT-PKR stress respon ...... ivation, leading to G₁ arrest.
@nl
prefLabel
The RAX/PACT-PKR stress respon ...... tivation, leading to G₁ arrest
@en
The RAX/PACT-PKR stress respon ...... ivation, leading to G₁ arrest.
@nl
P2093
P2860
P356
P1433
P1476
The RAX/PACT-PKR stress respon ...... tivation, leading to G₁ arrest
@en
P2093
Jaime Christian
Richard L Bennett
W Stratford May
P2860
P304
P356
10.4161/CC.11.2.18999
P577
2012-01-15T00:00:00Z