Cancer-associated alteration of pericentromeric heterochromatin may contribute to chromosome instability. - Test2 - elhamkhani - TriplyDB

Cancer-associated alteration of pericentromeric heterochromatin may contribute to chromosome instability.

Cancer-associated alteration of pericentromeric heterochromatin may contribute to chromosome instability.

http://www.wikidata.org/entity/Q39443543

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Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases KDM4/JMJD2 histone demethylases: epigenetic regulators in cancer cells Heterochromatin instability in cancer: from the Barr body to satellites and the nuclear periphery Epigenetic Histone Marks of Extended Meta-Polycentric Centromeres of Lathyrus and Pisum Chromosomes KDM4B/JMJD2B is a p53 target gene that modulates the amplitude of p53 response after DNA damage.Replication of alpha-satellite DNA arrays in endogenous human centromeric regions and in human artificial chromosome A portable BRCA1-HAC (human artificial chromosome) module for analysis of BRCA1 tumor suppressor function.A unique chromatin complex occupies young α-satellite arrays of human centromeres.Functional epialleles at an endogenous human centromere.The histone 3 lysine 9 methyltransferase inhibitor chaetocin improves prognosis in a rat model of high salt diet-induced heart failure.Aberrant reduction of telomere repetitive sequences in plasma cell-free DNA for early breast cancer detection.Cancer-predisposition gene KLLN maintains pericentric H3K9 trimethylation protecting genomic stability ETS transcription factor ERG cooperates with histone demethylase KDM4A.The CINs of the centromere.PREditOR: a synthetic biology approach to removing heterochromatin from cells p53 promotes repair of heterochromatin DNA by regulating JMJD2b and SUV39H1 expression.Jumonji domain-containing protein 2B silencing induces DNA damage response via STAT3 pathway in colorectal cancer.Pericentric and centromeric transcription: a perfect balance required.Transcription and ncRNAs: at the cent(rome)re of kinetochore assembly and maintenance.The oncogenic potential of Jumonji D2 (JMJD2/KDM4) histone demethylase overexpression.Histone lysine demethylase (KDM) subfamily 4: structures, functions and therapeutic potential.Control of genetic stability by a new heterochromatin compaction pathway involving the Tip60 histone acetyltransferase.Widespread telomere instability in prostatic lesions.KDM4C (GASC1) lysine demethylase is associated with mitotic chromatin and regulates chromosome segregation during mitosis.Centromere Stability: The Replication Connection.Selective inhibition of pancreatic ductal adenocarcinoma cell growth by the mitotic MPS1 kinase inhibitor NMS-P715.Using human artificial chromosomes to study centromere assembly and function.Centromeric barrier disruption leads to mitotic defects in Schizosaccharomyces pombe.CENPT bridges adjacent CENPA nucleosomes on young human α-satellite dimers.Upregulation of PSMD10 caused by the JMJD2A histone demethylase.Machine Learning for Nuclear Mechano-Morphometric Biomarkers in Cancer Diagnosis.Maternal expression of the histone demethylase Kdm4a is crucial for pre-implantation development.Human Centromeres Produce Chromosome-Specific and Array-Specific Alpha Satellite Transcripts that Are Complexed with CENP-A and CENP-C.Unexpected conformational variations of the human centromeric chromatin complex.Cooperation between ETS variant 2 and Jumonji domain‑containing 2 histone demethylases.Non-B-form DNA is enriched at centromeres.Generation of a Synthetic Human Chromosome with Two Centromeric Domains for Advanced Epigenetic Engineering Studies.The JmjN domain as a dimerization interface and a targeted inhibitor of KDM4 demethylase activity.Human Artificial Chromosome with Regulated Centromere: A Tool for Genome and Cancer Studies Extraordinary Genome Instability and Widespread Chromosome Rearrangements During Vegetative Growth

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Cancer-associated alteration of pericentromeric heterochromatin may contribute to chromosome instability.

http://www.wikidata.org/entity/Q39443543

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Cancer-associated alteration o ...... ute to chromosome instability.

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Cancer-associated alteration o ...... ute to chromosome instability.

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Cancer-associated alteration o ...... ute to chromosome instability.

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Cancer-associated alteration o ...... ute to chromosome instability.

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Cancer-associated alteration o ...... ute to chromosome instability.

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Cancer-associated alteration o ...... ute to chromosome instability.

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Cancer-associated alteration o ...... ute to chromosome instability.

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B R Grimes

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B-S Herbert

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P2860

Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases

Centrosome amplification drives chromosomal instability in breast tumor development.

Centromeric chromatin exhibits a histone modification pattern that is distinct from both euchromatin and heterochromatin

Aberrant overexpression of satellite repeats in pancreatic and other epithelial cancers

Centromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromere

Assembly and characterization of heterochromatin and euchromatin on human artificial chromosomes

Selective Inhibitors of the JMJD2 Histone Demethylases: Combined Nondenaturing Mass Spectrometric Screening and Crystallographic Approaches

Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

Molecular portraits of human breast tumours

Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer

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