Constitutive ERK activity induces downregulation of tristetraprolin, a major protein controlling interleukin8/CXCL8 mRNA stability in melanoma cells.
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Hallmarks of cancer and AU-rich elementsFeedback Regulation of Kinase Signaling Pathways by AREs and GREsThe control of inflammation via the phosphorylation and dephosphorylation of tristetraprolin: a tale of two phosphatasesBrf1 posttranscriptionally regulates pluripotency and differentiation responses downstream of Erk MAP kinaseControl by a hair's breadth: the role of microRNAs in the skinRegulation of the mRNA half-life in breast cancerBiased signaling in naturally occurring mutations in human melanocortin-3 receptor gene.Concise review: custodians of the transcriptome: how microRNAs guard stemness in squamous epithelia.CREB targets define the gene expression signature of malignancies having reduced levels of the tumor suppressor tristetraprolinInteraction with Pyruvate Kinase M2 Destabilizes Tristetraprolin by Proteasome Degradation and Regulates Cell Proliferation in Breast Cancer.LPS-induced production of TNF-α and IL-6 in mast cells is dependent on p38 but independent of TTPmiR-29a inhibition normalizes HuR over-expression and aberrant AU-rich mRNA stability in invasive cancer.Low tristetraprolin expression promotes cell proliferation and predicts poor patients outcome in pancreatic cancer.Tristetraprolin (TTP): interactions with mRNA and proteins, and current thoughts on mechanisms of action.Tristetraprolin expression and microRNA-mediated regulation during simian immunodeficiency virus infection of the central nervous systemTristetraprolin disables prostate cancer maintenance by impairing proliferation and metabolic function.Tristetraprolin: roles in cancer and senescence.Multiple functions of tristetraprolin/TIS11 RNA-binding proteins in the regulation of mRNA biogenesis and degradation.Post-transcriptional control of cytokine gene expression in health and disease.Rapid proteasomal degradation of posttranscriptional regulators of the TIS11/tristetraprolin family is induced by an intrinsically unstructured region independently of ubiquitination.Dysregulation of TTP and HuR plays an important role in cancers.Post-transcriptional regulation of cytokine and growth factor signaling in cancer.Depletion of tristetraprolin in breast cancer cells increases interleukin-16 expression and promotes tumor infiltration with monocytes/macrophages.A synonymous polymorphism of the Tristetraprolin (TTP) gene, an AU-rich mRNA-binding protein, affects translation efficiency and response to Herceptin treatment in breast cancer patients.Reconstructing cancer drug response networks using multitask learning.Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA.The role of RNA-binding protein tristetraprolin in cancer and immunity.Cigarette smoke and its component acrolein augment IL-8/CXCL8 mRNA stability via p38 MAPK/MK2 signaling in human pulmonary cells.
P2860
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P2860
Constitutive ERK activity induces downregulation of tristetraprolin, a major protein controlling interleukin8/CXCL8 mRNA stability in melanoma cells.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Constitutive ERK activity indu ...... A stability in melanoma cells.
@en
Constitutive ERK activity indu ...... A stability in melanoma cells.
@nl
type
label
Constitutive ERK activity indu ...... A stability in melanoma cells.
@en
Constitutive ERK activity indu ...... A stability in melanoma cells.
@nl
prefLabel
Constitutive ERK activity indu ...... A stability in melanoma cells.
@en
Constitutive ERK activity indu ...... A stability in melanoma cells.
@nl
P2093
P2860
P1476
Constitutive ERK activity indu ...... NA stability in melanoma cells
@en
P2093
Christine Bourcier
Gilles Pagès
Nathalie Mazure
Paola Griseri
Renaud Grépin
P2860
P304
P356
10.1152/AJPCELL.00506.2010
P577
2011-05-18T00:00:00Z