about
The ambiguous base-pairing and high substrate efficiency of T-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymeraseExtinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesisViral quasispecies evolutionDrug discovery technologies and strategies for Machupo virus and other New World arenaviruses.Mutagenesis-mediated decrease of pathogenicity as a feature of the mutant spectrum of a viral population.Arenavirus variations due to host-specific adaptation.Characterization of synthetic Chikungunya viruses based on the consensus sequence of recent E1-226V isolatesNovel Arenavirus Entry Inhibitors Discovered by Using a Minigenome Rescue System for High-Throughput Drug Screening.Identification and Mechanism of Action of a Novel Small-Molecule Inhibitor of Arenavirus Multiplication.Evaluation of the anti-arenaviral activity of the subtilisin kexin isozyme-1/site-1 protease inhibitor PF-429242.Determination and Therapeutic Exploitation of Ebola Virus Spontaneous Mutation Frequency.Highlights in antiviral drug research: antivirals at the horizon.Host cell factors as antiviral targets in arenavirus infection.Arenaviruses and lethal mutagenesis. Prospects for new ribavirin-based interventions.Current drug discovery strategies against arenavirus infections.Targeting virulence mechanisms for the prevention and therapy of arenaviral hemorrhagic fever.Targeting the "cytokine storm" for therapeutic benefit.Efficacy of Favipiravir Alone and in Combination With Ribavirin in a Lethal, Immunocompetent Mouse Model of Lassa Fever.Novel drug discovery approaches for treating arenavirus infections.Effective lethal mutagenesis of influenza virus by three nucleoside analogs.Inhibition of arenavirus by A3, a pyrimidine biosynthesis inhibitor.Sodium hydrogen exchangers contribute to arenavirus cell entry.The PI3K/Akt pathway contributes to arenavirus budding.Arenavirus Genome Rearrangement for the Development of Live Attenuated Vaccines.Favipiravir elicits antiviral mutagenesis during virus replication in vivo.Changes in protein domains outside the catalytic site of the bacteriophage Qβ replicase reduce the mutagenic effect of 5-azacytidine.Mechanism of RNA synthesis initiation by the vesicular stomatitis virus polymerase.Protective Effect of Anti-Phosphatidylserine Antibody in a Guinea Pig Model of Advanced Hemorrhagic Arenavirus Infection.Interactome analysis of the lymphocytic choriomeningitis virus nucleoprotein in infected cells reveals ATPase Na+/K+ transporting subunit Alpha 1 and prohibitin as host-cell factors involved in the life cycle of mammarenaviruses.Mechanism of action of ribavirin in anti-HCV regimens: new insights for an age-old question?A Highly Conserved Leucine In Mammarenavirus Matrix Z Protein Is Required For Z Interaction With The Virus L Polymerase And Z Stability In Cells Harboring An Active Viral Ribonucleoprotein.Antiviral Effect of Ribavirin against HCV Associated with Increased Frequency of G-to-A and C-to-U Transitions in Infectious Cell Culture Model.Nucleobases and corresponding nucleosides display potent antiviral activities against dengue virus possibly through viral lethal mutagenesis.Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis
P2860
Q21089768-C3863FAF-DB05-4D3A-970E-99AFC295E667Q21132564-B00AF8BC-8968-4AA5-B2F6-4783D7CA5364Q27013917-2AB131ED-9799-4164-840F-E77689642B66Q34274569-7ED18BBB-22F6-44FD-B551-DAC33E6CF027Q34326649-78101AF2-E101-4FC1-B75D-82FB92609851Q34647553-DD89653E-AFFD-48E5-80B5-D871E122AAAAQ34926408-187A184C-CC5C-4400-BDAE-83439D59C5C4Q35652155-078D0CC4-634D-4A8E-AC32-574559EBCE2EQ35751585-B0A73AD6-5BB0-4634-AAEF-77C699607B31Q35774829-84BBB786-DF04-47FD-93FC-3D4AC75EF084Q36736898-CE0CCD10-0373-4BF0-997E-94007F1107DBQ38007145-3A666147-53F0-4E26-8F95-429FC3627EFBQ38061425-9E888B25-BEAB-468A-A4D5-4B0EB3EE474DQ38064285-476AF7BE-0B08-4C2E-A227-1DC53FB2519FQ38067504-9A06862F-0782-44B3-BE00-F76B2E856359Q38069359-64066140-4C00-4CE8-B413-D74DF25BEF42Q38071254-3C2741ED-AD64-47E2-B33E-1713DBE41931Q38565357-16C4D814-2293-446A-B661-135C1B2AA5B3Q38735837-34F73B4B-5744-4DD0-A4D2-F3EAEF83CCA8Q38919847-506831E0-B890-4C10-A575-0B4850E9EE58Q39066377-40CC5A62-92DE-4438-B4E2-98426F884303Q39068701-90C35D24-B6E9-4CFF-B61A-443CAAC4D176Q39394363-59914298-7963-4061-84D5-76DC8D9A3858Q40156113-807816FB-6C62-48E9-88B0-5CE1CD90BDCBQ41693281-A78F6839-E54C-4A5E-A153-BE92675E7C90Q42138232-93574B4D-C703-43CC-A63D-D2B155CDF78EQ42591165-49F4C4A7-A5C3-40B9-8147-CEC092B9C0BEQ47105747-632BC12B-6BC3-4852-A14B-83C6A7563ED1Q50238755-3E598876-80C2-4F25-A000-A378AE7D58C4Q50548636-C00A80A5-4FDA-4306-A577-98A1AF3B54D9Q52625016-086EA35E-3A25-480D-AEB8-BBA565071D73Q52653197-C09E0292-555C-4943-A98D-8820E06B02C9Q54232437-DDD5BBE4-62B4-4440-8D4C-C1AEFD42923BQ57469924-EC4417D6-4E94-47B5-8B04-116E4E257CFB
P2860
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Ribavirin can be mutagenic for arenaviruses.
@en
Ribavirin can be mutagenic for arenaviruses.
@nl
type
label
Ribavirin can be mutagenic for arenaviruses.
@en
Ribavirin can be mutagenic for arenaviruses.
@nl
prefLabel
Ribavirin can be mutagenic for arenaviruses.
@en
Ribavirin can be mutagenic for arenaviruses.
@nl
P2093
P2860
P50
P356
P1433
P1476
Ribavirin can be mutagenic for arenaviruses
@en
P2093
Héctor Moreno
Isabel Gallego
Juan Carlos de la Torre
P2860
P304
P356
10.1128/JVI.00614-11
P407
P577
2011-05-11T00:00:00Z