Lipofection of purified adeno-associated virus Rep68 protein: toward a chromosome-targeting nonviral particle.
about
Efficient integration of recombinant adeno-associated virus DNA vectors requires a p5-rep sequence in cis.Development of animal models for adeno-associated virus site-specific integration.Conditional site-specific integration into human chromosome 19 by using a ligand-dependent chimeric adeno-associated virus/Rep protein.A chimeric protein containing the N terminus of the adeno-associated virus Rep protein recognizes its target site in an in vivo assay.Adeno-associated virus (AAV) site-specific recombination does not require a Rep-dependent origin of replication within the AAV terminal repeat.The innate immune sensor LGP2 activates antiviral signaling by regulating MDA5-RNA interaction and filament assembly.A p5 integration efficiency element mediates Rep-dependent integration into AAVS1 at chromosome 19.Herpes simplex virus type 1/adeno-associated virus rep(+) hybrid amplicon vector improves the stability of transgene expression in human cells by site-specific integration.Site-specific integration mediated by a hybrid adenovirus/adeno-associated virus vector.p53 inhibits adeno-associated viral vector integrationPreferential integration of adeno-associated virus type 2 into a polypyrimidine/polypurine-rich region within AAVS1.Targeting site-specific chromosome integration.Targeting antibodies to the cytoplasm.Non-viral adeno-associated virus-based platform for stable expression of antibody combination therapeutics.A helper-dependent capsid-modified adenovirus vector expressing adeno-associated virus rep78 mediates site-specific integration of a 27-kilobase transgene cassette.Selective cleavage of AAVS1 substrates by the adeno-associated virus type 2 rep68 protein is dependent on topological and sequence constraints.Site-specific integration of an adeno-associated virus vector plasmid mediated by regulated expression of rep based on Cre-loxP recombination.Characteristics of the adeno-associated virus preintegration site in human chromosome 19: open chromatin conformation and transcription-competent environment.Charge-to-alanine mutagenesis of the adeno-associated virus type 2 Rep78/68 proteins yields temperature-sensitive and magnesium-dependent variants.Effects of Cellular Methylation on Transgene Expression and Site-Specific Integration of Adeno-Associated Virus.
P2860
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P2860
Lipofection of purified adeno-associated virus Rep68 protein: toward a chromosome-targeting nonviral particle.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Lipofection of purified adeno- ...... e-targeting nonviral particle.
@en
Lipofection of purified adeno- ...... e-targeting nonviral particle.
@nl
type
label
Lipofection of purified adeno- ...... e-targeting nonviral particle.
@en
Lipofection of purified adeno- ...... e-targeting nonviral particle.
@nl
prefLabel
Lipofection of purified adeno- ...... e-targeting nonviral particle.
@en
Lipofection of purified adeno- ...... e-targeting nonviral particle.
@nl
P2093
P2860
P1433
P1476
Lipofection of purified adeno- ...... me-targeting nonviral particle
@en
P2093
C Toniatti
G Roscilli
P Delmastro
S Lamartina
P2860
P304
P407
P577
1998-09-01T00:00:00Z