Polo-like kinase-1 as a novel target in neoplastic mast cells: demonstration of growth-inhibitory effects of small interfering RNA and the Polo-like kinase-1 targeting drug BI 2536.
about
Pharmacological treatment options for mast cell activation diseaseIdentification of potential synthetic lethal genes to p53 using a computational biology approachSmall-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia AML.Chronic mast cell leukemia (MCL) with KIT S476I: a rare entity defined by leukemic expansion of mature mast cells and absence of organ damage.Identification of bromodomain-containing protein-4 as a novel marker and epigenetic target in mast cell leukemia.Drug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells.The JAK2/STAT5 signaling pathway as a potential therapeutic target in canine mastocytoma.Infliction of proteotoxic stresses by impairment of the unfolded protein response or proteasomal inhibition as a therapeutic strategy for mast cell leukemia.The KIT and PDGFRA switch-control inhibitor DCC-2618 blocks growth and survival of multiple neoplastic cell types in advanced mastocytosis.
P2860
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P2860
Polo-like kinase-1 as a novel target in neoplastic mast cells: demonstration of growth-inhibitory effects of small interfering RNA and the Polo-like kinase-1 targeting drug BI 2536.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Polo-like kinase-1 as a novel ...... nase-1 targeting drug BI 2536.
@en
Polo-like kinase-1 as a novel ...... nase-1 targeting drug BI 2536.
@nl
type
label
Polo-like kinase-1 as a novel ...... nase-1 targeting drug BI 2536.
@en
Polo-like kinase-1 as a novel ...... nase-1 targeting drug BI 2536.
@nl
prefLabel
Polo-like kinase-1 as a novel ...... nase-1 targeting drug BI 2536.
@en
Polo-like kinase-1 as a novel ...... nase-1 targeting drug BI 2536.
@nl
P2093
P2860
P50
P1433
P1476
Polo-like kinase-1 as a novel ...... nase-1 targeting drug BI 2536.
@en
P2093
Hans-Peter Horny
Irina Mirkina
Karina Schuch
Karoline V Gleixner
Leonhard Müllauer
Michael Willmann
Peter Valent
Veronika Ferenc
Viviane Winter
Winfried F Pickl
P2860
P304
P356
10.3324/HAEMATOL.2010.031328
P577
2011-01-17T00:00:00Z