Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38 - Test2 - elhamkhani - TriplyDB

Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38

Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38

http://www.wikidata.org/entity/Q39647641

about

Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization Hyperosmotic stress-induced ATF-2 activation through Polo-like kinase 3 in human corneal epithelial cells In situ proximity ligation detection of c-Jun/AP-1 dimers reveals increased levels of c-Jun/Fra1 complexes in aggressive breast cancer cell lines in vitro and in vivo Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK Transcriptional switch by activating transcription factor 2-derived peptide sensitizes melanoma cells to apoptosis and inhibits their tumorigenicity Phosphorylation of Activation Transcription Factor-2 at Serine 121 by Protein Kinase C Controls c-Jun-mediated Activation of Transcription Neurotrophin-regulated signalling pathways Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells The regulatory role of activating transcription factor 2 in inflammation HSF-1 interacts with Ral-binding protein 1 in a stress-responsive, multiprotein complex with HSP90 in vivo Activation and interaction of ATF2 with the coactivator ASC-2 are responsive for granulocytic differentiation by retinoic acid p27 suppresses cyclooxygenase-2 expression by inhibiting p38β and p38δ-mediated CREB phosphorylation upon arsenite exposure miRNA Alterations Modify Kinase Activation In The IGF-1 Pathway And Correlate With Colorectal Cancer Stage And Progression In Patients Identification of New Candidate Genes and Chemicals Related to Esophageal Cancer Using a Hybrid Interaction Network of Chemicals and Proteins Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferation Pairwise network mechanisms in the host signaling response to coxsackievirus B3 infection.Systems analysis of circadian time-dependent neuronal epidermal growth factor receptor signaling.A novel role for calcium/calmodulin kinase II within the brainstem pedunculopontine tegmentum for the regulation of wakefulness and rapid eye movement sleep.Emerging roles of ATF2 and the dynamic AP1 network in cancer.Loss of ATF2 function leads to cranial motoneuron degeneration during embryonic mouse development A cytoplasmic negative regulator isoform of ATF7 impairs ATF7 and ATF2 phosphorylation and transcriptional activity The unfolded protein response and the phosphorylations of activating transcription factor 2 in the trans-activation of il23a promoter produced by β-glucans Activating transcription factor 2 (ATF2) controls tolfenamic acid-induced ATF3 expression via MAP kinase pathways.Evidence that TMEM67 causes polycystic kidney disease through activation of JNK/ERK-dependent pathways.Microarray characterization of gene expression changes in blood during acute ethanol exposure c-Jun NH(2)-terminal kinase is essential for the regulation of AP-1 by tumor necrosis factor.Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells.Inhibition of the protein kinase MK-2 protects podocytes from nephrotic syndrome-related injury Cdk1-mediated phosphorylation of human ATF7 at Thr-51 and Thr-53 promotes cell-cycle progression into M phase.Reduced levels of ATF-2 predispose mice to mammary tumors.ATF-2 regulates fat metabolism in Drosophila.ATF2 is required for amino acid-regulated transcription by orchestrating specific histone acetylation.Critical role of N-terminal end-localized nuclear export signal in regulation of activating transcription factor 2 (ATF2) subcellular localization and transcriptional activity.ATF2 - at the crossroad of nuclear and cytosolic functions.Inheritance and memory of stress-induced epigenome change: roles played by the ATF-2 family of transcription factors Glatiramer acetate treatment negatively regulates type I interferon signaling.Rit GTPase regulates a p38 MAPK-dependent neuronal survival pathway Drosophila ATF-2 regulates sleep and locomotor activity in pacemaker neurons.ATF2 on the double - activating transcription factor and DNA damage response protein.The epidermal growth factor receptor increases cytokine production and cutaneous inflammation in response to ultraviolet irradiation.

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Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38

http://www.wikidata.org/entity/Q39647641

description

2002 nî lūn-bûn

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

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2002年论文

@zh

2002年论文

@zh-cn

name

Growth factors can activate AT ...... f Thr69 through RalGDS-Src-p38

@en

Growth factors can activate AT ...... Thr69 through RalGDS-Src-p38.

@nl

type

label

Growth factors can activate AT ...... f Thr69 through RalGDS-Src-p38

@en

Growth factors can activate AT ...... Thr69 through RalGDS-Src-p38.

@nl

prefLabel

Growth factors can activate AT ...... f Thr69 through RalGDS-Src-p38

@en

Growth factors can activate AT ...... Thr69 through RalGDS-Src-p38.

@nl

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The EMBO Journal

P1476

Growth factors can activate AT ...... f Thr69 through RalGDS-Src-p38

@en

P2093

Corina van der Burgt

http://www.w3.org/2001/XMLSchema#string

D Margriet Ouwens

http://www.w3.org/2001/XMLSchema#string

Gerard C M van der Zon

http://www.w3.org/2001/XMLSchema#string

J Antonie Maassen

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Jan Schouten

http://www.w3.org/2001/XMLSchema#string

Johannes L Bos

http://www.w3.org/2001/XMLSchema#string

Klaas Kooistra

http://www.w3.org/2001/XMLSchema#string

Nancy D de Ruiter

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P2860

The N-terminal transactivation domain of ATF2 is a target for the co-operative activation of the c-jun promoter by p300 and 12S E1A

ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation

c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms

Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions.

Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity

ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents

ATF-2 contains a phosphorylation-dependent transcriptional activation domain

Control of cell cycle progression by c-Jun is p53 dependent

Signal transduction by the JNK group of MAP kinases

A human nuclear-localized chaperone that regulates dimerization, DNA binding, and transcriptional activity of bZIP proteins

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3782-3793

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10.1093/EMBOJ/CDF361

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14

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21

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2002-07-01T00:00:00Z

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232770621

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12110590

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phosphorylation

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126107

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