about
Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferationThe crystal structure of DehI reveals a new alpha-haloacid dehalogenase fold and active-site mechanismConstraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognitionStructural basis of binding by cyclic nonphosphorylated peptide antagonists of Grb7 implicated in breast cancer progressionContribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotidesA Molecular Switch Governs the Interaction between the Human Complement Protease C1s and Its Substrate, Complement C4Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target1H NMR studies of the effects of glycosylation on the C-terminal pentapeptide of peptide T.NMR analysis of G7-18NATE, a nonphosphorylated cyclic peptide inhibitor of the Grb7 adapter protein.Conformational stability studies of a stapled hexa-β3-peptide library.The binding of TIA-1 to RNA C-rich sequences is driven by its C-terminal RRM domain.Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly.Preparation and crystallization of the Grb7 SH2 domain in complex with the G7-18NATE nonphosphorylated cyclic inhibitor peptide.Different modes of interaction by TIAR and HuR with target RNA and DNARNA recognition and stress granule formation by TIA proteins.RBM5 is a male germ cell splicing factor and is required for spermatid differentiation and male fertilityMutation and crystallization of the first KH domain of human polycytosine-binding protein 1 (PCBP1) in complex with DNA.Elucidation of a C-rich signature motif in target mRNAs of RNA-binding protein TIAR.Cooperative interplay of let-7 mimic and HuR with MYC RNA.Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.Distinct binding properties of TIAR RRMs and linker region.Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and diseasePreparation of crystals for characterizing the Grb7 SH2 domain before and after complex formation with a bicyclic peptide antagonist.Domain-specific phosphomimetic mutation allows dissection of different protein kinase C (PKC) isotype-triggered activities of the RNA binding protein HuR.Interaction of the replication terminator protein of Bacillus subtilis with DNA probed by NMR spectroscopy.Context-dependent role of Grb7 in HER2+ve and triple-negative breast cancer cell lines.The discovery of phenylbenzamide derivatives as Grb7-based antitumor agents.Interaction of the non-phosphorylated peptide G7-18NATE with Grb7-SH2 domain requires phosphate for enhanced affinity and specificity.Structural characterization of Staphylococcus aureus biotin protein ligase and interaction partners: an antibiotic targetBenzopyrazine derivatives: A novel class of growth factor receptor bound protein 7 antagonists.Uptake of a cell permeable G7-18NATE contruct into cells and binding with the Grb-7-SH2 domain.The intracellular and nuclear-targeted delivery of an antiandrogen drug by carrier peptides.Insight into the Selectivity of the G7-18NATE Inhibitor Peptide for the Grb7-SH2 Domain Target.Synthesis of an analog of the thyroid hormone-binding protein transthyretin via regioselective chemical ligation.Role of interfacial hydrophobic residues in the stabilization of the leucine zipper structures of the transcription factors c-Fos and c-Jun.Identification of PLA(2) and alpha-neurotoxin proteins in the venom of Pseudonaja affinis (dugite).Synthesis and structural analysis of the N-terminal domain of the thyroid hormone-binding protein transthyretin.Design and testing of bicyclic inhibitors of Grb7--are two cycles better than one?A functional comparison of the venom of three Australian jellyfish--Chironex fleckeri, Chiropsalmus sp., and Carybdea xaymacana--on cytosolic Ca2+, haemolysis and Artemia sp. lethality.Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting.
P50
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P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Jacqueline A Wilce
@nl
Jacqueline A Wilce
@sl
Jacqueline A. Wilce
@en
Jacqueline A. Wilce
@es
type
label
Jacqueline A Wilce
@nl
Jacqueline A Wilce
@sl
Jacqueline A. Wilce
@en
Jacqueline A. Wilce
@es
prefLabel
Jacqueline A Wilce
@nl
Jacqueline A Wilce
@sl
Jacqueline A. Wilce
@en
Jacqueline A. Wilce
@es
P1053
N-5018-2017
P106
P21
P31
P3829
P496
0000-0002-8344-2626