Mutant HSPB8 causes motor neuron-specific neurite degeneration.
about
Charcot-Marie-Tooth disease and intracellular trafficCrystal Structure of R120G Disease Mutant of Human αB-Crystallin Domain Dimer Shows Closure of a GrooveChaperonopathies: Spotlight on Hereditary Motor NeuropathiesAxonal Neuropathies due to Mutations in Small Heat Shock Proteins: Clinical, Genetic, and Functional Insights into Novel MutationsThe specificity of the interaction between αB-crystallin and desmin filaments and its impact on filament aggregation and cell viability.The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases.A novel transgenic mouse model of Chinese Charcot-Marie-Tooth disease type 2L.Highly immunoreactive IgG antibodies directed against a set of twenty human proteins in the sera of patients with amyotrophic lateral sclerosis identified by protein array.Non-Neuronal Cells Are Required to Mediate the Effects of Neuroinflammation: Results from a Neuron-Enriched Culture System.Aberrant Autophagic Response in The Muscle of A Knock-in Mouse Model of Spinal and Bulbar Muscular Atrophy.Molecular genetics of charcot-marie-tooth disease: from genes to genomes.Transcriptional induction of the heat shock protein B8 mediates the clearance of misfolded proteins responsible for motor neuron diseases.Pharmacoinformatic and molecular docking studies reveal potential novel antidepressants against neurodegenerative disorders by targeting HSPB8.Recent advances in the genetics of hereditary axonal sensory-motor neuropathies type 2.Large potentials of small heat shock proteins.The Role of the Protein Quality Control System in SBMA.A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8.Hsp70 - a master regulator in protein degradation.HspB5/αB-crystallin increases dendritic complexity and protects the dendritic arbor during heat shock in cultured rat hippocampal neurons.L-3-n-Butylphthalide Protects HSPB8 K141N Mutation-Induced Oxidative Stress by Modulating the Mitochondrial Apoptotic and Nrf2 Pathways.Developmental expression pattern of Hspb8 mRNA in the mouse brain: analysis through online databases.Downregulation of heat shock protein B8 decreases osteogenic differentiation potential of dental pulp stem cells during in vitro proliferation.A recurrent WARS mutation is a novel cause of autosomal dominant distal hereditary motor neuropathy.HspB8 expression in brain tissue after cerebral ischemic reperfusion and atorvastatin intervention in Sprague-Dawley rats.Mitochondrial deficits and abnormal mitochondrial retrograde axonal transport play a role in the pathogenesis of mutant Hsp27-induced Charcot Marie Tooth Disease.HspB8 mutation causing hereditary distal motor neuropathy impairs lysosomal delivery of autophagosomes.HSPB1 and HSPB8 in inherited neuropathies: study of an Italian cohort of dHMN and CMT2 patients.
P2860
Q26824841-0B7F34A0-E67B-47C3-B646-87262E5D3FF5Q27666994-BF2CBF33-B023-4C9B-8E8C-71E376636F7AQ28072171-2D8FD4E3-1B19-4188-8ECB-CD4762A39C0DQ29147507-706C3CFF-B079-4F79-BC80-123B7FE0E037Q30539278-191997DF-9FE6-472B-AB6A-6876FCB7070CQ33819258-AE658566-F44F-4B41-BDBE-3AF47B7459C8Q34095817-B512A81A-DA05-415F-9503-5224F0B6AD7AQ35107697-6A4AFAD6-8A77-4822-81D6-ACB44CB012C4Q35898735-E62E2CAD-FF38-4CAF-AC9D-F1C5063ABBC7Q36189002-BB6FDCF2-82E6-4F6E-888F-7F16763D8B0EQ36493294-B597C1B6-0681-4DA0-8D4A-55A8D1B3A768Q36670771-1919EDCE-157D-4FD5-BBB6-7C4A12433DE4Q36900533-2014DEEF-6627-4AC4-970F-78A8378247F4Q37843794-A5097BC9-B51A-4804-B6BA-D692FAB8BCC2Q37947562-20C08050-AC12-491D-A718-D0E64FEA37C0Q38634366-74FC3344-CA78-4BA0-801E-D30D1D1E5632Q38638620-2A4C4D28-9F0A-4ACB-BDD1-5780A0F80AE3Q39428376-328AC88E-A866-474F-BB5B-9CDAEB7DDBA1Q40796472-D8D15481-F62F-47CB-993B-BC4685F6140EQ40988486-E4F0A95E-E60F-4881-ACC6-E03B44271DFCQ42499843-CB269B03-9268-4F79-A180-C6590C2EE53DQ47265982-07CC8EFA-BF3A-4DA4-9F2C-F313ED642F5BQ47927418-7F11444C-5017-437E-BC2F-3AB2BCFAD23DQ48626057-700D5081-C0F3-408F-9D7D-92219D91A5F2Q50194442-30C19E89-96DC-4DD3-8E8F-5E717870195DQ53402953-40B656AF-B308-49E9-83C8-85E2ED3F6360Q54333720-0FBB2245-E295-4C67-9EA0-96AC0E09A552
P2860
Mutant HSPB8 causes motor neuron-specific neurite degeneration.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Mutant HSPB8 causes motor neuron-specific neurite degeneration.
@en
Mutant HSPB8 causes motor neuron-specific neurite degeneration.
@nl
type
label
Mutant HSPB8 causes motor neuron-specific neurite degeneration.
@en
Mutant HSPB8 causes motor neuron-specific neurite degeneration.
@nl
prefLabel
Mutant HSPB8 causes motor neuron-specific neurite degeneration.
@en
Mutant HSPB8 causes motor neuron-specific neurite degeneration.
@nl
P2093
P2860
P50
P356
P1476
Mutant HSPB8 causes motor neuron-specific neurite degeneration
@en
P2093
Ines Dierick
Jyothsna Krishnan
Peter De Jonghe
Sofie Goethals
Sophie Janssens
Vicky De Winter
Vincent Timmerman
Wim Robberecht
P2860
P304
P356
10.1093/HMG/DDQ234
P577
2010-06-10T00:00:00Z