Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cells. - Test2 - elhamkhani - TriplyDB

Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cells.

Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cells.

http://www.wikidata.org/entity/Q39735805

about

Myosin VI and its interacting protein LMTK2 regulate tubule formation and transport to the endocytic recycling compartment.BREK/LMTK2 is a myosin VI-binding protein involved in endosomal membrane trafficking T6BP and NDP52 are myosin VI binding partners with potential roles in cytokine signalling and cell adhesion.How are the cellular functions of myosin VI regulated within the cell?Role of the epithelial cell-specific clathrin adaptor complex AP-1B in cell polarity Myosin motor proteins are involved in the final stages of the secretory pathways Myosins in cell junctions Myosin VI regulates actin structure specialization through conserved cargo-binding domain sites Posttranslational modifications, localization, and protein interactions of optineurin, the product of a glaucoma gene Loss of optineurin in vivo results in elevated cell death and alters axonal trafficking dynamics Use of fluorescence-activated vesicle sorting for isolation of Naked2-associated, basolaterally targeted exocytic vesicles for proteomics analysis Myosin-1c regulates the dynamic stability of E-cadherin-based cell-cell contacts in polarized Madin-Darby canine kidney cells.Myosin VI is required for targeted membrane transport during cytokinesis.Mutant huntingtin impairs post-Golgi trafficking to lysosomes by delocalizing optineurin/Rab8 complex from the Golgi apparatus Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant.Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane.Myosin-X functions in polarized epithelial cells.Myosin VI small insert isoform maintains exocytosis by tethering secretory granules to the cortical actin.Rab8 interacts with distinct motifs in alpha2B- and beta2-adrenergic receptors and differentially modulates their transport.Polarized sorting and trafficking in epithelial cells Myosin VI and optineurin are required for polarized EGFR delivery and directed migration.Direct interactions of adaptor protein complexes 1 and 2 with the copper transporter ATP7A mediate its anterograde and retrograde trafficking Induction of autophagy in rats upon overexpression of wild-type and mutant optineurin gene.Reconstitution of the ERG Gene Expression Network Reveals New Biomarkers and Therapeutic Targets in ERG Positive Prostate Tumors Involvement of unconventional myosin VI in myoblast function and myotube formation.Protein kinase C δ regulates the release of collagen type I from vascular smooth muscle cells via regulation of Cdc42.Myosin VI and vinculin cooperate during the morphogenesis of cadherin cell cell contacts in mammalian epithelial cells.Dynamic exchange of myosin VI on endocytic structures Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation Genetic characterization of the Drosophila jaguar322 mutant reveals that complete myosin VI loss of function is not lethal.Myosin VI Contains a Compact Structural Motif that Binds to Ubiquitin Chains.Myosin VI in skeletal muscle: its localization in the sarcoplasmic reticulum, neuromuscular junction and muscle nuclei.Cellular and molecular biology of optineurin.Hepatocyte polarity Analysis of AQP4 trafficking vesicle dynamics using a high-content approach.Coiled-coil-mediated dimerization is not required for myosin VI to stabilize actin during spermatid individualization in Drosophila melanogaster.Regulation of membrane trafficking in polarized epithelial cells.Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain Role of membrane traffic in the generation of epithelial cell asymmetry.Taking the scenic route: biosynthetic traffic to the plasma membrane in polarized epithelial cells

P2860

Q24301155-FE6B94B2-B919-40DE-B18C-EAF04B8217D6 Q24324187-67D6B113-8A6E-4596-806D-978ADF61AFA1 Q24650918-FCB845FF-E58E-4325-ACA2-C257E0E80EF1 Q24658390-BC694768-8C7D-40FD-9F74-CCFFEB1A5A01 Q26750773-D01E3C4C-2FD2-4638-B607-695A00E15701 Q26850080-4CD641FD-44EA-41FB-9960-53159AEDE7F3 Q27004163-389010E7-4FD0-4D14-B484-59A4E423D9D1 Q27329752-BF03F296-2383-420F-9B9A-9B423C961B11 Q27334656-993F21D5-A0EE-4EBF-8C4C-A1C495D6431B Q27336244-770F698F-2EBE-4D67-96CF-1A2789A2AE34 Q28910487-6811DD9E-1CBD-45DA-9A77-7F64BE6B9BD5 Q30416190-17FB2D52-49AB-41D9-8736-94444A38D03C Q30480755-005C7D36-A25F-4D40-BBF0-7A62261C5AC6 Q30486228-7905B540-8C0C-4FB3-A2DC-B7DF4C913035 Q30493294-49863199-CAF5-4168-A099-E3B549E53812 Q30497821-673038C3-B056-4B99-A3FC-4088AB11504F Q30513859-840AC119-8F72-4DD6-86F9-19A5D039BC03 Q30534452-B979F513-6727-4C91-B284-50FB63EB8467 Q33924469-4C4C64B7-A1F1-4F23-94E1-7E5A67D3282F Q34270230-41524B44-870F-477D-AAFB-E6821FB11B5E Q34575273-3950D0B0-C243-472D-AEE9-E6020901509E Q35253046-01172529-8A17-4242-9B24-E2A0FCAA2C3B Q35599430-7A9CA401-94CD-4554-BC30-D50B2F0355BA Q35631603-611A9A5B-16CE-4338-8E07-1F751033E976 Q35747240-E79AEE94-CD02-4517-9F40-DE6B393BDE6E Q35953865-BEAD82C5-60DD-4CCC-82C7-D89A378396CF Q36119767-65CB05B3-26E8-4426-A47F-BEA43B79BFE9 Q36385806-6CBF8EA4-F008-4250-AE2F-D788C2983681 Q36567245-6B50F209-322F-43B5-A384-865669F50BDF Q36665969-B1F405A6-FA8C-4356-A9FB-45ADE120D66C Q36723224-0597EC7B-2D25-4EE6-AAF7-7ADB4A5E32AA Q36850126-2318C2DB-0518-4198-8524-7E936B42EE25 Q36905164-623BFBAF-83A5-444E-A829-22E7F3411BF4 Q36972087-38E00568-FEDA-4B9C-9671-4EA4FC7ABCAE Q37023376-3BBC3EA2-1E52-4F0C-A022-07865C58DC58 Q37035184-3066AACC-1E79-43EA-8077-E1297D5DFA23 Q37087769-75BCAB6E-8EC9-4090-9EEA-995B017EF577 Q37135682-E4B5434E-B481-4D27-8E67-60557A65153F Q37167379-1457F9E6-A2A5-4E90-8C89-C442634CBD82 Q37488634-91E9148C-F09A-42B1-9239-3E05514F6811

P2860

Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cells.

http://www.wikidata.org/entity/Q39735805

description

2007 nî lūn-bûn

@nan

2007年の論文

@ja

2007年学术文章

@wuu

2007年学术文章

@zh-cn

2007年学术文章

@zh-hans

2007年学术文章

@zh-my

2007年学术文章

@zh-sg

2007年學術文章

@yue

2007年學術文章

@zh

2007年學術文章

@zh-hant

name

Myosin VI is required for sort ...... omain in polarized MDCK cells.

@en

Myosin VI is required for sort ...... omain in polarized MDCK cells.

@nl

type

label

Myosin VI is required for sort ...... omain in polarized MDCK cells.

@en

Myosin VI is required for sort ...... omain in polarized MDCK cells.

@nl

prefLabel

Myosin VI is required for sort ...... omain in polarized MDCK cells.

@en

Myosin VI is required for sort ...... omain in polarized MDCK cells.

@nl

P1433

Q39735805-4D07E648-BA20-4957-8C9C-8C26DF7D5830

P1476

Q39735805-1D2FF421-EA9E-47D9-9ECB-3C5C527A098E

P2093

Q39735805-047B4208-64DC-4EF8-BAF5-6EA459A3B870

Q39735805-52B1652F-87A7-4E0E-BF5B-631D48E16F9E

Q39735805-6AE3624A-C6E9-4D78-A532-BF82F8CC7F13

Q39735805-7BAB2023-72D1-4D60-B331-D1A7A7FE8B9B

Q39735805-9EBA04F8-3324-4747-A434-00563EA41071

P2860

Q39735805-01285860-94C3-4859-87C3-C399514CB032

Q39735805-0997EF37-EF81-4CD0-9E16-E66951163A49

Q39735805-0B74CAB6-AABD-4D2C-98DC-0A5E40ECA4DA

Q39735805-0F0D75C6-893D-49EB-AE0E-E957BB0BBFBB

Q39735805-167626C7-4A6E-45B2-956B-89A061F74005

Q39735805-1A063075-934D-415F-B52B-208A1A2A86B7

Q39735805-202CD3C3-CEC8-4A45-BB95-00D76A086D1A

Q39735805-30764CCF-04F3-4137-83BF-82C090F1CB66

Q39735805-30A7E227-C158-4C23-A980-1D214E3E3FA5

Q39735805-350F7271-896F-4534-8AF8-5D520172212F

P304

Q39735805-77D7F609-2CCC-4359-8ED5-06253F9EA480

P31

Q39735805-227290C1-9C11-4E22-A559-1C67964D5614

P356

Q39735805-169F6E1F-31AE-4533-ADC6-67EE64BB1C43

P407

Q39735805-89756BAE-0E43-4716-9A90-7237F8D7F059

P433

Q39735805-348B4862-A7A7-4677-A0CD-93F03AAC72DE

P478

Q39735805-205EC4E7-C14B-4C9F-92CE-D817C0E55F4D

P577

Q39735805-37917E42-38B2-4E39-9437-150FD8DB2E27

P5875

Q39735805-9DAB2BCB-93D0-4A01-AD46-F5CA0223900C

P698

Q39735805-A4B7DC0D-F9EB-4383-94B1-B9B58B32A23B

P932

Q39735805-476BE5A8-6558-4363-AA22-2E1DEF6B0D96

P356

P1433

Journal of Cell Biology

P1476

Myosin VI is required for sort ...... omain in polarized MDCK cells.

@en

P2093

Claudia Puri

http://www.w3.org/2001/XMLSchema#string

Folma Buss

http://www.w3.org/2001/XMLSchema#string

Gudrun Ihrke

http://www.w3.org/2001/XMLSchema#string

John Kendrick-Jones

http://www.w3.org/2001/XMLSchema#string

Josephine Sui-Yan Au

http://www.w3.org/2001/XMLSchema#string

P2860

The localization of myosin VI at the golgi complex and leading edge of fibroblasts and its phosphorylation and recruitment into membrane ruffles of A431 cells after growth factor stimulation

Mu1B, a novel adaptor medium chain expressed in polarized epithelial cells

Myosin VI is an actin-based motor that moves backwards

Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosis.

Myosin VI binds to and localises with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton

Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis

Myo6 facilitates the translocation of endocytic vesicles from cell peripheries

Differential recognition of tyrosine-based basolateral signals by AP-1B subunit mu1B in polarized epithelial cells.

Distribution and function of AP-1 clathrin adaptor complexes in polarized epithelial cells

Rab8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma membrane

P304

103-114

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1083/JCB.200608126

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

177

http://www.w3.org/2001/XMLSchema#string

P577

2007-04-02T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51385463

http://www.w3.org/2001/XMLSchema#string

P698

17403927

http://www.w3.org/2001/XMLSchema#string

P932

2064115

http://www.w3.org/2001/XMLSchema#string