Beta2 integrins are required for skin homing of primed T cells but not for priming naive T cells.
about
The multiple faces of leukocyte interstitial migrationCRK proteins selectively regulate T cell migration into inflamed tissues.Wound-healing defect of CD18(-/-) mice due to a decrease in TGF-beta1 and myofibroblast differentiation.Loss of beta2-integrin-mediated cytoskeletal linkage reprogrammes dendritic cells to a mature migratory phenotype.CD18 deficiency protects against multiple low-dose streptozotocin-induced diabetes.T cell-extrinsic CD18 attenuates antigen-dependent CD4+ T cell activation in vivo.Prevention of leukocyte migration to inflamed skin with a novel fluorosugar modifier of cutaneous lymphocyte-associated antigen.Lymphocyte trafficking to inflamed skin--molecular mechanisms and implications for therapeutic target molecules.CD18 is required for optimal lymphopenia-induced proliferation of mouse T cells.Reversion mutations in patients with leukocyte adhesion deficiency type-1 (LAD-1)Beta2 integrins separate graft-versus-host disease and graft-versus-leukemia effectsNeutrophil-selective CD18 silencing using RNA interference in vivoLessons from rare maladies: leukocyte adhesion deficiency syndromes.Effector CD8 T cell trafficking within the liverSenescent BALB/c mice are able to develop resistance to Leishmania major infection.LFA-1-mediated T cell costimulation through increased localization of TCR/class II complexes to the central supramolecular activation cluster and exclusion of CD45 from the immunological synapseLocation, location, location: the impact of migratory heterogeneity on T cell function.The molecular cues regulating immune cell trafficking.Inflamed lymphatic endothelium suppresses dendritic cell maturation and function via Mac-1/ICAM-1-dependent mechanism.Adaptive immune response to model antigens is impaired in murine leukocyte-adhesion deficiency-1 revealing elevated activation thresholds in vivoActivated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation.Unique and redundant roles of alpha4 and beta2 integrins in kinetics of recruitment of lymphoid vs myeloid cell subsets to the inflamed peritoneum revealed by studies of genetically deficient mice.Beta(2) integrin deficiency yields unconventional double-negative T cells distinct from mature classical natural killer T cells in mice.Junctional adhesion molecule (JAM)-B supports lymphocyte rolling and adhesion through interaction with alpha4beta1 integrin.T cell- and B cell-independent adaptive immunity mediated by natural killer cells.
P2860
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P2860
Beta2 integrins are required for skin homing of primed T cells but not for priming naive T cells.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年學術文章
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name
Beta2 integrins are required f ...... not for priming naive T cells.
@en
Beta2 integrins are required f ...... not for priming naive T cells.
@nl
type
label
Beta2 integrins are required f ...... not for priming naive T cells.
@en
Beta2 integrins are required f ...... not for priming naive T cells.
@nl
prefLabel
Beta2 integrins are required f ...... not for priming naive T cells.
@en
Beta2 integrins are required f ...... not for priming naive T cells.
@nl
P2093
P2860
P50
P356
P1476
Beta2 integrins are required f ...... not for priming naive T cells.
@en
P2093
Cord Sunderkötter
Georg Varga
Gunther Pendl
Meike Steinert
Stefan Beissert
Stephan Grabbe
Stephan Seeliger
Thomas Schwarz
Thorsten Peters
Wilhelm Bloch
P2860
P304
P356
10.1172/JCI0211703
P407
P577
2002-01-01T00:00:00Z