Glucose regulated protein 94 is required for muscle differentiation through its control of the autocrine production of insulin-like growth factors
about
Optimizing IGF-I for skeletal muscle therapeuticsRole of IGF-I signaling in muscle bone interactionsThe stress protein/chaperone Grp94 counteracts muscle disuse atrophy by stabilizing subsarcolemmal neuronal nitric oxide synthase.The endoplasmic reticulum protein folding factory and its chaperones: new targets for drug discovery?The insulin-like growth factor (IGF)-I E-peptides are required for isoform-specific gene expression and muscle hypertrophy after local IGF-I production.Proteomic plasma membrane profiling reveals an essential role for gp96 in the cell surface expression of LDLR family members, including the LDL receptor and LRP6.Increased expression of Gp96 by HBx-induced NF-κB activation feedback enhances hepatitis B virus productionTargeted loss of GHR signaling in mouse skeletal muscle protects against high-fat diet-induced metabolic deterioration.Deletion of muscle GRP94 impairs both muscle and body growth by inhibiting local IGF production.Limitation of individual folding resources in the ER leads to outcomes distinct from the unfolded protein response.Role of the unfolded protein response, GRP78 and GRP94 in organ homeostasis.A Human Variant of Glucose-Regulated Protein 94 That Inefficiently Supports IGF Production.GRP94 in ER quality control and stress responsesDiversity in the origins of proteostasis networks--a driver for protein function in evolutionDevelopment of a Grp94 inhibitor.Deletion of growth hormone receptors in postnatal skeletal muscle of male mice does not alter muscle mass and response to pathological injury.Characterization of the Grp94/OS-9 chaperone-lectin complex.Sparing of muscle mass and function by passive loading in an experimental intensive care unit model.
P2860
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P2860
Glucose regulated protein 94 is required for muscle differentiation through its control of the autocrine production of insulin-like growth factors
description
2009 nî lūn-bûn
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2009年の論文
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年學術文章
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name
Glucose regulated protein 94 i ...... of insulin-like growth factors
@en
Glucose regulated protein 94 i ...... f insulin-like growth factors.
@nl
type
label
Glucose regulated protein 94 i ...... of insulin-like growth factors
@en
Glucose regulated protein 94 i ...... f insulin-like growth factors.
@nl
prefLabel
Glucose regulated protein 94 i ...... of insulin-like growth factors
@en
Glucose regulated protein 94 i ...... f insulin-like growth factors.
@nl
P2093
P2860
P921
P1476
Glucose regulated protein 94 i ...... of insulin-like growth factors
@en
P2093
Catherine Makarewich
Davide Eletto
Elisabeth R Barton
Olga Ostrovsky
Yair Argon
P2860
P304
P356
10.1016/J.BBAMCR.2009.11.005
P577
2009-11-13T00:00:00Z