The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis.
about
Oncogenic Intra-p53 Family Member Interactions in Human CancersMutant p53 and ETS2, a Tale of ReciprocityMutant p53: One, No One, and One Hundred ThousandThe Contrived Mutant p53 Oncogene - Beyond Loss of FunctionsThe rebel angel: mutant p53 as the driving oncogene in breast cancer.Mutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers.E2F1 promotes angiogenesis through the VEGF-C/VEGFR-3 axis in a feedback loop for cooperative induction of PDGF-B.The inflammatory cytokine TNFα cooperates with Ras in elevating metastasis and turns WT-Ras to a tumor-promoting entity in MCF-7 cells.Mutant p53-induced up-regulation of mitogen-activated protein kinase kinase 3 contributes to gain of functionIncreased ID4 expression, accompanied by mutant p53 accumulation and loss of BRCA1/2 proteins in triple-negative breast cancer, adversely affects survival.Bioinformatic detection of E47, E2F1 and SREBP1 transcription factors as potential regulators of genes associated to acquisition of endometrial receptivityPreferential binding of hot spot mutant p53 proteins to supercoiled DNA in vitro and in cells.E47 and Id1 interplay in epithelial-mesenchymal transitionDifferential expression of ID4 and its association with TP53 mutation, SOX2, SOX4 and OCT-4 expression levels.Mutant p53 attenuates the anti-tumorigenic activity of fibroblasts-secreted interferon betamicroRNAs: short non-coding bullets of gain of function mutant p53 proteins.Clinical implications of the quantitative detection of ID4 gene methylation in myelodysplastic syndrome.Changes in the expression of DNA-binding/differentiation protein inhibitors in neurons and glial cells of the gerbil hippocampus following transient global cerebral ischemia.ID4 mediates proliferation of astrocytes after excitotoxic damage in the mouse hippocampusID proteins regulate diverse aspects of cancer progression and provide novel therapeutic opportunities.MicroRNAs: short non-coding players in cancer chemoresistance.Primed for cancer: Li Fraumeni Syndrome and the pre-cancerous nicheGain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expressionMutant p53 cooperates with ETS2 to promote etoposide resistance.MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of functionMutant p53: one name, many proteins.Hypomethylation of DNA-binding inhibitor 4 serves as a potential biomarker in distinguishing acquired tamoxifen-refractory breast cancerIdentification of post-transcriptional regulatory networks during myeloblast-to-monocyte differentiation transition.Mutant p53-R273H mediates cancer cell survival and anoikis resistance through AKT-dependent suppression of BCL2-modifying factor (BMF).TP53 Mutational Analysis Enhances the Prognostic Accuracy of IHC4 and PAM50 Assays.MicroRNAs, wild-type and mutant p53: more questions than answers.Gender, mutant p53 and PML: a growing "affaire" in tumor suppression and oncogenesis.Mutant p53-Notch1 Signaling Axis Is Involved in Curcumin-Induced Apoptosis of Breast Cancer Cells.The consequence of oncomorphic TP53 mutations in ovarian cancer.Differential regulation of the REGγ-proteasome pathway by p53/TGF-β signalling and mutant p53 in cancer cells.Cancer cell-secreted IGF2 instigates fibroblasts and bone marrow-derived vascular progenitor cells to promote cancer progression.Understanding wild-type and mutant p53 activities in human cancer: new landmarks on the way to targeted therapies.miRNA in the regulation of ion channel/transporter expression.TP53 mutants in the tower of babel of cancer progression.Mutant p53 in cancer: new functions and therapeutic opportunities.
P2860
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P2860
The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
The execution of the transcrip ...... omotes tumor neo-angiogenesis.
@en
The execution of the transcrip ...... omotes tumor neo-angiogenesis.
@nl
type
label
The execution of the transcrip ...... omotes tumor neo-angiogenesis.
@en
The execution of the transcrip ...... omotes tumor neo-angiogenesis.
@nl
prefLabel
The execution of the transcrip ...... omotes tumor neo-angiogenesis.
@en
The execution of the transcrip ...... omotes tumor neo-angiogenesis.
@nl
P2093
P2860
P50
P356
P1476
The execution of the transcrip ...... romotes tumor neo-angiogenesis
@en
P2093
Eytan Domany
Giovanni Blandino
Marcella Mottolese
Paola Muti
Sabrina Strano
Stefania Dell'Orso
P2860
P2888
P304
P356
10.1038/NSMB.1669
P50
P577
2009-09-27T00:00:00Z