Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth.
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Targeting cellular metabolism to improve cancer therapeuticsTargeting metabolism in breast cancer: How far we can go?Lactate dehydrogenase A in cancer: a promising target for diagnosis and therapyRestoration of mitochondria function as a target for cancer therapyPleiotropic role of HSF1 in neoplastic transformationHeat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an updateGambogic acid identifies an isoform-specific druggable pocket in the middle domain of Hsp90βOmniSearch: a semantic search system based on the Ontology for MIcroRNA Target (OMIT) for microRNA-target gene interaction data.Warburg effect in chemosensitivity: targeting lactate dehydrogenase-A re-sensitizes taxol-resistant cancer cells to taxolHER2/ErbB2 activates HSF1 and thereby controls HSP90 clients including MIF in HER2-overexpressing breast cancerOncogene activation induces metabolic transformation resulting in insulin-independence in human breast cancer cells.JMJD2A promotes the Warburg effect and nasopharyngeal carcinoma progression by transactivating LDHA expressionOMIT: dynamic, semi-automated ontology development for the microRNA domainMicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression.Regulation of cyclooxygenase-2 expression by heat: a novel aspect of heat shock factor 1 function in human cells.HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers.Cardiac-specific over-expression of epidermal growth factor receptor 2 (ErbB2) induces pro-survival pathways and hypertrophic cardiomyopathy in mice.Emerging metabolic targets in cancer therapyOvercoming trastuzumab resistance in breast cancer by targeting dysregulated glucose metabolism.Mutant p53 - Heat Shock Response Oncogenic Cooperation: A New Mechanism of Cancer Cell Survival.High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer.Recent Advances on Luminescent Enhancement-Based Porous Silicon Biosensors.Polymorphism rs4919510:C>G in mature sequence of human microRNA-608 contributes to the risk of HER2-positive breast cancer but not other subtypesProteotoxic stress of cancer: implication of the heat-shock response in oncogenesis.Utility of serum LDH isoforms in the assessment of mycobacterium tuberculosis induced pathology in TB patients of Sahariya tribeHeat shock factor Hsf1 cooperates with ErbB2 (Her2/Neu) protein to promote mammary tumorigenesis and metastasis.Transcriptome profiling of bovine inner cell mass and trophectoderm derived from in vivo generated blastocysts.Twist promotes reprogramming of glucose metabolism in breast cancer cells through PI3K/AKT and p53 signaling pathways.Overexpression of HER-2 in MDA-MB-435/LCC6 Tumours is Associated with Higher Metabolic Activity and Lower Energy Stress.Receptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolismOverexpression of ErbB2 renders breast cancer cells susceptible to 3-BrPA through the increased dissociation of hexokinase II from mitochondrial outer membrane.Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression.Heat shock factor 1 (HSF1) controls chemoresistance and autophagy through transcriptional regulation of autophagy-related protein 7 (ATG7)Stalling the engine of resistance: targeting cancer metabolism to overcome therapeutic resistance.The oncogene HER2/neu (ERBB2) requires the hypoxia-inducible factor HIF-1 for mammary tumor growth and anoikis resistanceImplication of heat shock factors in tumorigenesis: therapeutical potential.Prognostic value of peritumoral heat-shock factor-1 in patients receiving resection of hepatocellular carcinoma.Increased pretreatment levels of serum LDH and ALP as poor prognostic factors for nasopharyngeal carcinoma.Targeting Metabolic Remodeling in Triple Negative Breast Cancer in a Murine Model.Relationship between tumor heterogeneity measured on FDG-PET/CT and pathological prognostic factors in invasive breast cancer.
P2860
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P2860
Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Upregulation of lactate dehydr ...... er cell glycolysis and growth.
@en
Upregulation of lactate dehydr ...... er cell glycolysis and growth.
@nl
type
label
Upregulation of lactate dehydr ...... er cell glycolysis and growth.
@en
Upregulation of lactate dehydr ...... er cell glycolysis and growth.
@nl
prefLabel
Upregulation of lactate dehydr ...... er cell glycolysis and growth.
@en
Upregulation of lactate dehydr ...... er cell glycolysis and growth.
@nl
P2093
P356
P1433
P1476
Upregulation of lactate dehydr ...... cer cell glycolysis and growth
@en
P2093
P2888
P304
P356
10.1038/ONC.2009.229
P407
P50
P577
2009-08-10T00:00:00Z